Metaplasia Flashcards
Metaplasia
Differentiated cells of one type are replaced by a different kind
- common event
- relatively slow, over multiple mitotic generations
Epithelial metaplasia could be _____ to _______
Secreting to non-secreting
Squamous metaplasia
- inflammation: CDV dog, trachea
- endocrine: Sertoli cell tumor of dog prostate
- nutritional vitamin A deficiency
Metaplasia is a _____ change in cells
Phenotypic
Modulation
Rapid reversible cell change
- no division required
Distemper virus results in ______
Squamous metaplasia
- severe necrosis
- no cilia, no goblet cells
Chicken esophagus can develop ______
Squamous metaplasia of ducts
- nutritional vitamin A deficiency
- keratin debris forms nodules
Hyperplasia in the prostate of a dog can develop _____
Squamous metaplasia
- Sertoli cell tumor
Recurrent airway obstruction/heaves
Airway hyperplasia and metaplasia
- goblet cells affected
Chronic otitis externa
Ceruminous gland hyperplasia
- dysplastic ossification: chronic inflammation
Herniated disk
Intervertebral disk degeneration
- form of mesnchymal metaplasia
- chondrocytes in irregular lacunae
- variable matrix
- chondroid metaplasia
Myxoid metaplasia-endocardiosis
Mesenchymal metaplasia
- spindle cells in pale blue matrix
Dural osseos metaplasia is an example of ______
Mesenchymal metaplasia
