METABOLISM L7 Flashcards

I. Metabolism and E change - CC catabolism and anabolism - SEQ how ATP drives work - SEQ E flow through ecosystems II. Enzymes - SEQ enzymatic activity - HD factors that effect enzyme activity III. Redox reactions - CC oxidation and reduction - SEQ NAD+ function

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1
Q

metabolism

A
  • sum of all chemical reactions and E transformations in an organism
  • regulated to maintain homeostasis
  • emergent property of life
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2
Q

metabolic pathway

A
  • begins with specific molecule, ends with product

- each step catalyzed by specific enzyme

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3
Q

anabolic pathway

A
  • synthetic
  • making bonds
  • requires E
  • simple to complex molecules
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4
Q

catabolic pathway

A
  • breaks bonds
  • releases E
  • complex to simple molecules
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5
Q

kinetic energy

A
  • E of motion
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6
Q

potential energy

A
  • stored E, capacity to do work
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7
Q

thermodynamics

A
  • study of E transformations
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8
Q

1st law of thermodynamics

A
  • E cannot be created or destroyed
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9
Q

2nd law of thermodynamics

A
  • every E transfer increases entropy in the universe
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10
Q

entropy

A
  • measure of disorder

- randomness

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11
Q

free energy

A
  • E available to do work
  • can’t measure directly
  • can determine how G changes during reactions
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12
Q

exergonic

A
  • tend to be catabolic
  • energy released
  • spontaneous (-G)
  • often involves ATP hydrolysis
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13
Q

endergonic

A
  • tend to be anabolic
  • energy required
  • nonspontaneous (+G)
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14
Q

ATP

A
  • “high energy” molecule

- primary energy molecule of the cell

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15
Q

globular proteins

A
  • often have grooves due to tertiary or quaternary structure
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16
Q

active site

A
  • region that interacts with substrate
17
Q

substrate

A
  • any substance acted upon by an enzyme
18
Q

induced fit

A
  • enzyme changes shape after binding substrate for better fit
  • facilitates breaking/forming bonds
19
Q

factors affecting enzyme activity

A
  • enzymes operate best at specific temp and pH
  • low temp: slow reaction
  • high temp: denature enzyme
20
Q

enzyme inhibition

A
  • enzymes can be inhibited or destroyed by certain chemicals
  • competitive: inhibitor binds to active site, excludes substrate
  • noncompetitive: inhibitors binds elsewhere, changes active site shape
21
Q

enzyme cofactors

A
  • enhance enzyme activity

- may bind to enzyme or substrate

22
Q

redox reactions

A
  • oxidation: donating e
  • reduction: accepting e
  • always coupled
23
Q

NAD+

A
  • oxidized state: NAD+
  • reduced state: NADH
  • NADH: stored E