CELL CYCLE L10 Flashcards

I. Organization of Cellular Genetic Material - CC chromosome structure and number II. SEQ, HD, CC steps of cell cycle

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1
Q

cell theory

A
  • all living cells made of one or more cells
  • cells are the basic organizational and functional units of all organisms
  • all cells come from other cells
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2
Q

unicellular

A
  • just reproduction
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3
Q

multicellular

A
  • growth and development
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4
Q

main function of cell division

A
  • distribute genetic material into daughter cells
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5
Q

genome

A
  • cells total genetic material
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6
Q

prokaryotes

A
  • usually 1 circular DNA molecule
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7
Q

eukaryotes

A
  • usually >1 linear DNA molecules
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8
Q

genes

A
  • informational unit of DNA
  • responsible for structure of all proteins in a cell
  • at locus
  • arranged linearly on chromosomes
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9
Q

chromosomes

A
  • “colored body”
  • DNA wrapped around proteins
  • highly organized
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10
Q

histones

A
  • proteins in eukaryotic cells that associate with DNA to form chromosomes
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11
Q

nucleosomes

A
  • 8 histones with 146 base pairs of DNA wrapped around adjacent nucleosomes linked by 60 base pairs
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12
Q

chromatin

A
  • DNA/protein complex in dispersed state
  • DNA usually in this state
  • condenses to chromosomes
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13
Q

chromosome structure

A
  • each has unique shape and size

- centromeres and telomeres

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14
Q

centromeres

A
  • constricted area

- site of spindle attachment

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15
Q

telomeres

A
  • end regions
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16
Q

haploid

A
  • (n)
  • number of distinct or different chromosomes
  • 1 of each chromosome
  • ex. gametes
17
Q

diploid

A
  • (2n)
  • 2 of each chromosome
  • same length, centromere location, genes
  • ex. somatic cells
18
Q

interphase

A
  • growth and synthesis
  • metabolically active
  • G1, S, G2
19
Q

G1

A
  • prepare for S phase
  • no DNA synthesis
  • growth and normal development
20
Q

S

A
  • synthesis

- chromosomes duplicated

21
Q

G2

A
  • DNA still as chromatin
  • high metabolic activity
  • 2 centrosomes
  • preparation for mitosis
22
Q

centrosome

A
  • region of microtubule organization
  • contains pair of centrioles
  • duplicates in G2
23
Q

M phase

A
  • mitosis and cytokinesis
24
Q

5 stages of mitosis

A
  • prophase
  • prometaphase
  • metaphase
  • anaphase
  • telophase
25
Q

prophase

A
  • chromosomes condense

- mitotic spindle forms

26
Q

prometaphase

A
  • nuclear membrane breaks down
  • fragments stored in vesicles for later use
  • nucleolus disappears
  • mitotic spindle elongates
27
Q

metaphase

A
  • chromosomes align at metaphase plate
28
Q

anaphase

A
  • sister chromatids separate and move to opposite poles
  • pulled by kinetochores
  • separase separates sister chromatids
  • after separation each chromatid is considered a chromosome
29
Q

telophase

A
  • chromosomes start to decondense
  • nuclear envelope reforms
  • new nuclei identical to parent nucleus
  • daughter cells genetically identical to parent
30
Q

cytokinesis

A
  • cytoplasmic division - 2 cells each with 1 nucleus