Metabolic pathways Flashcards

1
Q

Metabolic pathways are controlled

A

by the presence or absence of particular enzymes

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2
Q

Rates of enzymatic reactions can be controlled

A

by intracellular and extracellular signal molecules

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3
Q

anabolic pathways require

A

energy and involve biosynthetic process

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4
Q

catabolic pathways release

A

energy and involve the breakdown of molecules

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5
Q

Most metabolic reactions are

A

reversible and the presence of substrate or removal of product will drive a sequence of reaction in particular direction

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6
Q

Metabolic pathways can have

A

irreversible steps and alternative routes.

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7
Q

The activity of enzymes depends

A

of their flexible and dynamic shape.

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8
Q

substrate molecules have

A

an affinity for the active site of an enzyme

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9
Q

The enzymes is flexible and the substrate

A

can induce the active site to change shape by induced fit.

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10
Q

The active site can

A

orientate the substrate molecules so they fit more closely

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11
Q

The energy required to initiate a chemical reaction is

A

called the activation energy

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12
Q

Enzymes lower

A

activation energy

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13
Q

Products of the enzyme

A

have a low affinity for the active site of the enzyme , and are released.

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14
Q

The concentration of substrate and end product affect the

A

direction and rate of enzyme energy

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15
Q

Enzyme often act in

A

in groups or as multi-enzyme complexes

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16
Q

Non-competitive inhibition

A

involves the binding of molecules that change the shape of the enzyme and its active site, so that it can no longer combine with substrate molecules

17
Q

Competitive inhibition

A

involves competitive fort the active site of the enzyme form molecules that resemble the substrate

18
Q

competitive inhibition can be reduced by

A

by increasing substrate concentration

19
Q

Feedback inhibition is a method of

A

metabolic control in which the end product binds to an enzyme that catalyse a reaction early in the pathway