Metabolic Fuel Use: Exercising, Dieting, and Starvation Flashcards

1
Q

Calories per macromolecule

A

Carb - 4
Fat - 9
Protein - 4
Alcohol - 7

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2
Q

Respiration flow chart

A

Digest - circulate - cells - oxidation to CO2 and H2O - ATP - Energy

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3
Q

Glycolysis including location

A

Anaerobic breakdown of glucose in cytoplasm
2 ATP per glucose
Produce pyruvate

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4
Q

Krebs cycle including location

A

Mitochondria
Aerobic (needs by-products of aerobic ETC)
2 ATP per initial glucose

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5
Q

Ideal cellular respiration

A

1 glucose = 38 ATP

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6
Q

ETC

A

Aerobic

34 ATP per glucsoe

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7
Q

Carbohydrates

A

Partially oxidized

Glucose is predominant form in blood

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8
Q

Essential AA

A
PVT TIM HALL
Phenylalanine 
Valine
Threonine 
Tryptophan 
Isoleucine 
Methionine
Histidine 
Leucine 
Lysine
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9
Q

Conditionally essential AA

A

Arginine
Tyrosine
Cysteine

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10
Q

Lipids composed of

A

Triacylglycerols

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11
Q

Glycogen, protein, and triglyceride amount and %

A

Muscle (glycogen) - .15 kg (.4%)
Liver (glycogen) - .08 kg (.2%)
Protein - 6.0 and 14.4%
Triglyceride (adipose) - 15 and 85%

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12
Q

Why store energy as fat

A

More calories per kg, so less added weigth

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13
Q

In fed state,

A

Cellular respiration occurs in all cells
Triglycerides to adipose tissue
glucose to liver, muscles, and adipose tissue

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14
Q

Major fasting energy source

A

Hepatic glycogenolysis (breakdown of liver glycogen)

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15
Q

Minor fasting energy sources

A

Hepatic gluconeogenesis (synthesis of glucose)
Adipose release of fat
Protein degradation

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16
Q

Gluconeogenesis in liver

A

Lactate converted to pyruvate to glucose using FFA from adipose tissue

17
Q

Pyruvate can be converted to

A

Lactate

18
Q

In post-absorptive state,

A

Triglycerides broken down, ATP from ketones and fatty acids

19
Q

1 lb of adipose tissue

A

3500 calories

20
Q

1000 calories less per day `

A

lose 2 lbs per week

21
Q

BMI formula

A

Weight/ht^2 (kg/m)

WeightX704)/(height^2) (lb/in

22
Q

BMI thresholds

A

<18.5 - underweight
25 - overweight
40 - morbidly obese

23
Q

Fad diets typically result in

A

Degradation of muscle protein and liver glycogen

Water is excreted

24
Q

Weight loss more than 2 lbs per week is predominantly

A

Water

25
Q

Short-term E

A

Glycolysis…..5 to 3 mins

26
Q

Immediate energy

A

ATP - CP…seconds

27
Q

Long-term E

A

Aerobic…cellular respiration/ATP production

28
Q

Longer periods of exercise

A

Glycogen used initially, then switch to adipose fat breakdown

29
Q

Marasmus vs. cachexia

A

Malnutrition

Marasmus has no underlying disease state

30
Q

Priorities for blood supply

A

RBCs, brain, protein preservation

31
Q

First 4 hours

A

Exogenous glucose

32
Q

4-12 hours

A

Liver glycogen

33
Q

After about 2 days of starvation

A

Hepatic gluconeogenesis

Initially lactate from muscles, then FFA and then glycerol from adipose tissue

34
Q

When adipose stores used for energy source, _______ becomes main source for _______

A

Ketone bodies

Brain

35
Q

During starvation, is glucose still made? and why?

A

Yes, RBCs need it

36
Q

As adipose stores deplete, what happens

A

Protein degradation accelerates and leads to organ failure/death

37
Q

Diagnosis of malnutration

A
Insufficient energy intake 
Weight loss
Loss of muscle mass
Loss of sub1 fat
Edema 
Hand grip weakness
Plus history 

Two or more

38
Q

Cachexia occurs with

A

Pancreatic, lung, head/neck, GI cancer
Stroke
COPD