Disposition of Proteins Flashcards
Plasma membrane movement
Things can move laterally fairly freely
Transport across plasma membrane
Simple diffusion
Facilitated transport
Gated channels
Active transport
Vesicular transport
Endo and exocytosis
Lysosomes
Contain lyases and digest biomolecules
Mitochondria inner membrane
Highly impermeable…allows for buildup of protons for ATP generation
Most of mitochondria proteins are from
Cytosol
How are things moved out of mitochondria
Through outer membrane via receptor-mediated process
Peroxisomes
Single bilayer molecule
Oxidation reactions using molecular oxygen
Must import proteins
Nucleolus
Site of rRNA transcription and ribosome assembly
Nuclear envelope outer layer continuous with
RER
Nuclear pores allow
ribosomes and rRNA out and proteins in
SER
Synthesis of lipids and enzymes involved in drug and toxic substance metabolism
Makes steroid hormones
RER
Synthesis of proteins
Transports proteins to golgi
Modificiation - GPI anchors or N-linked glycosylation
Golgi Complex
Distribution center for proteins ands lipids from ER to plasma membrane and vesicles
Modifies oligosaccharides attached to asparagines, adds o-linked oligosaccharides to serines and threonines, add nano-6-P to proteins to move to lysosomes
Endosomes
Sorting centers for things that come from outside…send to golgi for use or destruction