Metabolic Diseases Flashcards

1
Q

Why don’t you want a cow too skinny when calving? Too fat?

A

Too skinny: Won’t have any body reserves to make milk

Too fat: will have

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2
Q

When does fatty liver syndrome occur?

A
  • Peaks at about 2 weeks post-parturition
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3
Q

What is ketosis/ acetonemia?

A
  • Abnormally high ketone body concentrations in the body/ body fluids
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4
Q

What is primary ketosis?

A

Negative energy balance especially in early lactation –> usually subclinical

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5
Q

What is secondary ketosis?

A

Ketosis related to anorexia due to some other disease

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6
Q

What are the clinical signs of ketosis

A
  • Decreased appetite and milk production
  • Hypocalcemia
  • Nervous form –> occurs post-partum, cow is biting at itself, excessively grooming itself, not producing milk
  • Ketone odors on breath, urine, milk
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7
Q

What are the clinical signs of ketosis

A
  • Decreased appetite and milk production
  • Hypocalcemia
  • Nervous form –> occurs post-partum, cow is biting at itself, excessively grooming itself, not producing milk
  • Ketone odors on breath, urine, milk
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8
Q

How do you diagnose ketosis?

A

Clinical signs and test for ketones in urine/ milk

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9
Q

What is the therapy for ketosis?

A
  • Stimulate gluconeogenesis
  • Increase utilization of blood glucose
  • Fix the underlying cause
  • Reduce plasma ketones and free fatty acids
  • Supplement the ration –> once they eat again, the problem should improve, give propylene glycol, glycerol, proprinate ** Dont’ overdose!!!!!!**
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10
Q

How do you prevent ketosis?

A
  • Maintain body condition from the dry period through calving
  • Encourage max dry matter intake
  • Feed balanced diet with high quality forage to early lactation cows
  • Minimize negative energy balance after calving
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11
Q

What is pregnancy toxemia?

A
  • Condition similar to ketosis –> don’t have enough energy to support gestation and milk production
  • Seen in beef cows and small ruminants
  • Due to chronic underfeeding during pregnancy, given poor quality forage with no supplemental grain/ energy
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12
Q

What is parturient paresis/ milk fever?

A
  • Hypocalcemia associated with parturition
  • Rapid milk production causes rapid depletion of serum ionized calcium
  • **Not actually a fever!!! **
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13
Q

Which dairy breed is most susceptible to milk fever?

A

Jersey, followed by Guernsey

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14
Q

What is the normal calcium levels in a cow?

A

9-12 mg/dL

- Below 9 is subclinical

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15
Q

What do you use to treat milk fever in a cow?

A
  • Use calcium borogluconate SQ
  • Basic restraint –> tie head to back leg
  • Give with an 18 G, 2” needle
  • cardiotoxic
  • Can give an electrolyte paste –> good but can be caustic
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16
Q

How do you know the calcium is working for milk fever?

A
  • The cow will eructate due to smooth muscle relaxation
  • Will appear bright and alert
  • Don’t allow the cow to get up too quickly, especially if on a slippery surface
  • Will usually need to give one bottle, in larger animals you may need two
17
Q

What is the most common mineral deficiency in cattle?

A

Phosphorous!

  • Copper is number 2 –> copper toxicity is common in the US
18
Q

In what cows do you see phosphorous deficiency?

A
  • Grazing cattle, young animals, and heavily lactating dairy cows
19
Q

What are some clinical signs of phosphorus deficiency?

A
  • Osteomalacia stiffness
  • Spontaneous fractures
  • Pica
  • Hemoglobinuria
20
Q

How do you treat phosphorous deficiency?

A
  • Dietary supplementaion
  • Sodium acid phosphate IV
  • Fertilize pasture with phosphorous –> best
21
Q

What other mineral deficiency is associated with phosphorus deficiency?

A
  • Magnesium
22
Q

What causes grass tetany?

A
  • Hypomagnesemia
23
Q

What are the clinical signs of grass tetany?

A
  • Hyperexcitability, hyperesthesia
  • ## Lateral recumbency with violent opisthotonus
24
Q

How do you treat grass tetany?

A
  • Mg hypophosphate
  • Calcium
  • Orally administered electrolyte paste
25
Q

How do you prevent grass tetany?

A
  • Mg supplementation, especially during winter
  • Pasture topdressing with magnesium
  • Phosphate