MESH POOL Flashcards

1
Q

Strawberry tongue

A

Scarlet fever and Kawasaki disease

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2
Q

MCC of UTI in women

A

E. coli

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3
Q

Cause of honeymoon cystitis

A

E. coli

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4
Q

Blindness due to scarring in a newborn

A

Chlamydia trachomatis

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5
Q

Hydrophobia in rabies infxn due to

A

Laryngeal spasm

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6
Q

Dohle bodies

A

Leukocytosis in chronic bacterial infection

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7
Q

MC type of Hodgkin lymphoma

A

Nodular sclerosis (NSHL) aka Classical Hodgkin Lymphoma

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8
Q

Pathologic finding in NSHL

A

Lacunar Reed Sternberg cell

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9
Q

Mott cells

A

Multiple myeloma

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10
Q

Russel bodies

A

Multiple myeloma

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11
Q

Renal finding in HIV

A

FSGN

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12
Q

Libmann Sacks endocarditis

A

SLE

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13
Q

Most specific antibody for SLE

A

Anti-Sm

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14
Q

Wire loop appearance of kidneys

A

SLE

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15
Q

MC class of renal disease in SLE

A

IV (diffuse proliferative lupus)

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16
Q

Achalasia on UGI series

A

Bird’s beak

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17
Q

Parasite associated with achalasia

A

T. cruzi

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18
Q

MC 1° CNS adult tumor

A

Glioblastoma multiforme

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19
Q

Homer Wright pseudorosettes

A

Neuroblastoma aka medulloblastoma

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20
Q

Flexner Wintersteiner rosettes

A

Retinoblastoma

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21
Q

Small vessel vasculitis, IgA deposition

A

HSP

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22
Q

Hallmark of HSP

A

Palpable purpura

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23
Q

Diffuse foot process effacement

A

Minimal change disease (MCD) aka lipoid nephrosis

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24
Q

MCD, response to steroids

A

Excellent

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25
Q

Smoker, leg claudication at rest

A

Buerger disease

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26
Q

MC location of MI

A

Transmural

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27
Q

MC vessel occluded in MI

A

LAD

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28
Q

Dengue patient, given FFP transfusion, 3 days developed fever, chills, jaundice. Agent?

A

Hepatitis C (BT-associated hepatitis)

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29
Q

MC cancers that metastasize to bone

A

Prostate and breast

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30
Q

Kidney finding in chronic hypertension

A

Nephrosclerosis

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31
Q

MC type of VSD

A

Membranous

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32
Q

MC location of Tb osteomyelitis

A

Thorax and lumbar

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33
Q

Defective cell eliminated from the body by

A

Apoptosis

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34
Q

Reid index is associated with

A

Bronchitis

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35
Q

MC type tetanus

A

Generalized

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36
Q

Funnel-shaped pelvis

A

Android

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37
Q

Aschoff body

A

Rheumatic fever

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38
Q

Mc Allman plaque

A

Rheumatic fever

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39
Q

Mc Allman plaque consists of

A

Caterpillar cells/Anitschkow cells

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40
Q

Child with greasy, frothy, bulky stools

A

Malabsorption syndrome

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41
Q

Characteristic BM finding in Aplastic Anemia

A

Abundant fat cells

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42
Q

(+) ground glass pattern with air bronchograms

A

RDS

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43
Q

Anti-TPO antibodies

A

Hashimoto’s thyroiditis

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44
Q

(+) linear anti-GBM deposits

A

Goodpasture’s syndrome

45
Q

Heart shaped vertebra

A

Thoracic

46
Q

Neoplasia associated with dysplastic nevus

A

Melanoma

47
Q

Crew cut xray

A

Beta thalasemia (bone marrow hyperplasia)

48
Q

Guarneri bodies

A

Inclusion bodies for Small Pox

49
Q

Donovan bodies

A

Granuloma inguinale

50
Q

Most number of RS (Reed-Sternberg) cells

A

Mixed type

51
Q

Varicella-zoster, the virus that causes chicken pox, can remain latent in the

A

Sensory ganglia

52
Q

HEART FAILURE CELLS

A

Hemosiderin-laden macrophages

53
Q

Hirano bodies

A

Alzheimer’s disease

54
Q

Sanded nuclei

A

Chronic hepatitis B virus infection

55
Q

Vignette: Obese woman with infertility, acne, alopecia, hirsuitism

A

PCOS/Stein-Leventhal syndrome

56
Q

MC cause of death after MI

A

Ventricular arrhthymia (ventricular fibrillation)

57
Q

RUSTY SPUTUM + ALCOHOLIC

A

S. pneumoniae

58
Q

Lobar pneumonia

A

S. pneumoniae

59
Q

Thymic aplasia

A

DiGeorge’s Disease

60
Q

4 years old, with recurrent otitis media, eczema, and thrombocytopenia from Strep pneumoniae. AND, he bleeds a lot. His IgM is low

A

WAS (Wiskott-Aldrich syndrome)

61
Q

Infection in a post renal transplant patient

A

CMV

62
Q

Presence of pneumatocoeles on chest radiograph

A

S. aureus

63
Q

A syndrome characterized by galactorrhea-amenorrhea not associated with pregnancy

A

Ahumada-del Castillo syndrome

64
Q

Intrauterine synechiae, typically occurring after curettage of the uterus, presenting as amenorrhea

A

Asherman syndrome

65
Q

Severe cerebral atrophy with two distinct features of neurofibrillary tangles and senile amyloid plaques is diagnostic of

A

Alzheimer’s disease

66
Q

Alzheimer’s disease, defective gene

A

APOE4 gene

67
Q

The most frequent cause of spontaneous subarachnoid hemorrhage

A

Ruptured berry aneurysm

68
Q

HPV that can cause cervical CA

A

HPV 16 and 18

69
Q

Proven to be a cause of skin cancer

A

Ultraviolet light exposure

70
Q

A5year old malnourished child with a month long history of voluminous watery stools. Came in due to petechia

A

Vitamin K deficiency

71
Q

A 33-year old woman undergoes an annual physical examination and there are no abnormal findings. A Pap smear was done as part of the pelvic examination. Cytologically, the cells obtained from the cervical smear show severe epithelial dysplasia. Which of the following statements best explains the significance of these findings?

A

The lesion could progress to invasive cervical carcinoma

72
Q

A 2 yo boy with a history of repeated transfusions came to you with exam findings of hepatosplenomegaly and prominent cheekbones. Where is the defect?

A

Globin synthesis

73
Q

Drug that is a known carcinogen

A

Griseofulvin

74
Q

Case of a boy with joint laxity, dislocation of the lens, high stature. Where is the defect?

A

Structural protein (MARFAN)

75
Q

Sea blue histiocytes

A

CML

76
Q

Case of a 4 year old boy with blood picture of spherocytes and reticulocytes.. Where is the defect?

A

RBC membrane (Hereditary spherocytosis)

77
Q

Indomethacin blocks

A

PG

78
Q

Gastric cancer most commonly occurs in

A

Lesser curvature

79
Q

Person with AIDS presents with deteriorating mental status. The cerebrospinal fluid revealed bright red organisms with India Ink. Which of the following is the most likely diagnosis?

A

Cryptococcosis

80
Q

A 30 year old male with obesity, diabetes mellitus, hypertension and problem with lipids. What is the
diagnosis?

A

Metabolic syndrome

81
Q

A 25 year old woman came in for amenorrhea of 2-3 months. Examination showed a uterine sized of 4-5
months. Pregnancy test was positive. Grape like clusters where found

A

Hydatidiform mole

82
Q

After recovering from a viral respiratory infection, 22-year old woman, weakness in distal extremities that rapidly ascends to involve proximal muscles, absent deep tendon reflexes, CSF protein to be increased, but very few cells are
present, biopsy of a peripheral nerve reveals inflammation and demyelination

A

GBS

83
Q

Lung cancer common in non-smokers

A

AdenoCA

84
Q

Case of MI. Earliest sign of necrosis

A

12 hours; 2-3 hours if tetrazolium salt solution used

85
Q

Case with red infarct. This occurs in

A

Lung

86
Q

A 50 year old who came in with pain on walking. Joint aspiration showed blue-black discoloration. What is
the deficiency?

A

Homogentisic acid oxidase

87
Q

Case of megaloblastic anemia. What vitamin deficiency would cause this?

A

Vit B12 and folate

88
Q

A 2 year old boy presented with a large well circumscribed abdominal mass involving both kidneys. Microscopic examination reveals epithelial tissues, blastema and mesenchymal tissues.

A

Wilm’s Tumor

89
Q

Most common type of renal cell cancer

A

Clear cell

90
Q

Which of the following is a common feature of all Hodgkin’s Lymphomas

A

RS cells

91
Q

Case of foul-smelling copious sputum with destruction of alveolar walls

A

Bronchiectasis

92
Q

A 30 yr woman with complains of problems with her vision and lactation even though she is not pregnant

A

Prolactinoma

93
Q

A woman with complains of tremors, weight loss and palpitations. Work-up showed infiltration of recti muscles with fibrous tissues.

A

Graves’ disease

94
Q

Patient with long- standing hypertension will most likely present with

A

Lacunar infarcts

95
Q

Montelukast acts by inhibiting

A

Leukotrienes

96
Q

Case of patient with microscopic findings of loss of differentiation of cells… (malignant transformation)

A

Anaplasia

97
Q

Microscopic findings that would point to papillary thyroid cancer

A

Psammoma bodies

98
Q

Typhoid ileitis is commonly due to untreated

A

Typhoid fever

99
Q

Patient with findings of hyperparathyroidism. Microscopic findings of fairly uniform polygonal cells with a small centrally placed nuclei.

A

Parathyroid adenoma

100
Q

An 8 yr old male came in with findings of a holosytolic murmur 5/6 on the 2nd parasternal border. Where is
the defect? (no mention of right or left… since this is pediatric- VSD?)

A

Membranous interventricular septum

101
Q

Squamous cell carcinoma of the esophagus most commonly occurs in

A

Middle third

102
Q

Test for diagnosis of SLE

A

Anti-dsDNA

103
Q

The inflammatory reaction seen in typhoid ileitis is composed mostly of

A

Mononuclear cells

104
Q

A 10 month old infant presented with a vaginal mass

A

Rhabdomyosarcoma

105
Q

Case of Alzheimer’s disease. What bodies can be seen in the hippocampus and purkinje cells?

A

Hirano bodies

106
Q

What is the most characteristic cell found in Rhabdomyoma?

A

Spider cell

107
Q

Case of someone undergoing a ct-scan with contrast. Mechanism of kidney injury after injection of contrast
medium

A

Direct kidney injury

108
Q

Percent of hepatocellular carcinoma from hepatitis B infection

A

More than 50%