Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Pathology > High-Yield Pathology, USMLE > Flashcards

High-Yield Pathology, USMLE Flashcards

1
Q

Associated Neoplasm: Down Syndrome

A

ALL, AML

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Associated Neoplasm: Xeroderma pegmetosum, albinism

A

Melanoma, basal cell carcinoma, and especially squamous cell carcinoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Associated Neoplasm: Chronic atrophic gastritis, pernicious anemia

A

Gastric Adenocarcinoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Associated Neoplasm: Tuberous sclerosis (facial angiofibroma, seizures, mental retardation)

A

Astrocytoma, Angiomyolipoma, and cardiac rhabdomyoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Associated Neoplasm: Actinic keratosis

A

Squamous Cell Carcinoma of skin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Associated Neoplasm: Barrett’s Esophagus

A

Esophageal Adenocarcinoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Associated Neoplasm: Plummer-Vinson Syndrome (atrophic glossitis, esophageal webs, anemia all due to Fe def)

A

Squamous Cell Carcinoma of esophagus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Associated Neoplasm: Cirrhosis

A

Hepatocellular Carcinoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Associated Neoplasm: Ulcerative Colitis

A

Colonic Adenocarcinoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Associated Neoplasm: Paget’s disease of the bone

A

Secondary osteosarcoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Associated Neoplasm: Immunodeficiency States

A

Malignant Lymphomas

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Associated Neoplasm: AIDS

A

Aggressive Malignant Lymphoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Associated Neoplasm: Autoimmune disease

A

Benign and Malignant Lymphomas

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Associated Neoplasm: Acanthosis Nigricans

A

Visceral Malignancy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Associated Neoplasm: Dysplastic Nevus

A

Malignant Melanoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Associated Neoplasm: Radiation Exposure

A

Sarcoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Associated Tumor: abl

Oncogene or Tumor suppressor?

A

CML

Oncogene

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Associated Tumor: c-myc

Oncogene or Tumor suppressor?

A

Burkitt’s lymphoma

Oncogene

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Associated Tumor: bcl-2

Oncogene or Tumor suppressor?

A

Follicular and undifferentiated lymphoma

Oncogene

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Associated Tumor: erb-B2

Oncogene or Tumor suppressor?

A

Breast, ovarian, and gastric carcinoma

Oncogene

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Associated Tumor: ras

Oncogene or Tumor suppressor?

A

colon carcinoma

Oncogene

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Associated Tumor: L-myc

Oncogene or Tumor suppressor?

A

Lung Cancer

Oncogene

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Associated Tumor: N-myc

Oncogene or Tumor suppressor?

A

Neuroblastoma

Oncogene

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Associated Tumor: ret

Oncogene or Tumor suppressor?

A

MEN II and III

Oncogene

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

Associated Tumor: c-kit

Oncogene or Tumor suppressor?

A

Gastrointestinal stromal tumor

Oncogene

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

Associated Tumor: Rb

Oncogene or Tumor Suppressor

A

Retinoblastoma, Osteosarcoma

Tumor Suppressor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

Associated Tumor: BRCA1

Oncogene or Tumor Suppressor

A

Breast and Ovarian Cancer

Tumor Suppressor

28
Q

Associated Tumor: BRCA2

Oncogene or Tumor Suppressor

A

Breast

Tumor Suppressor

29
Q

Associated Tumor: p53

Oncogene or Tumor Suppressor

A

Most cancers

Tumor Suppressor

30
Q

Associated Tumor: p16

Oncogene or Tumor Suppressor

A

Melonoma

Tumor Suppressor

31
Q

Associated Tumor: APC

Oncogene or Tumor Suppressor

A 
Colorectal Cancer (FAP)
Tumor Suppressor
32
Q

Associated Tumor: WT1

Oncogene or Tumor Suppressor

A

Wilm’s Tumor

Tumor Suppressor

33
Q

Associated Tumor: NF1

Oncogene or Tumor Suppressor

A

Neurofibromatosis Type 1

Tumor Suppressor

34
Q

Associated Tumor: NF2

Oncogene or Tumor Suppressor

A

Neurofibromatosis Type 2

Tumor Suppressor

35
Q

Associated Tumor: DPC

Oncogene or Tumor Suppressor

A

Pancreatic Cancer

Tumor Suppressor

36
Q

Associated Tumor: DCC

Oncogene or Tumor Suppressor

A

Colon Cancer

Tumor Suppressor

37
Q

Name the Neoplasm: Patient with Cushing’s syndrome

A

ACTH - Small Cell Lung Cancer

38
Q

Name the Neoplasm: Patient with SIADH

A

ADH - Small Cell Lung Cancer and Intracranial neoplasms

39
Q

Name the Neoplasm: Patient with Hypercalcemia

A

PTH - Squamous Cell Lung Carcinoma, renal cell carcinoma, and Breast Cancer

40
Q

Name the Neoplasm: Patient with Polycethemia

A

EPO - Renal Cell Carcinoma, hemangioblastoma

41
Q

Name the Neoplasm: Patient with Lambert-Eaton Syndrome (progressive weakness w/out facial involvement)

A

Antibodies against presynaptic Ca2+ channels and NMJ - Thymoma, Small Cell Lung Cancer

42
Q

Name the Neoplasm: Patient with Gout and/or urate nephropathy

A

Excessive Nucleic Acids - Leukemias and lymphomas

43
Q

Psammoma bodies are found in these 4 cancers:

A
  1. Papillary adenocarcinoma of the thyroid
  2. Serous papillary cystadenocarcinoma of ovary
  3. Meningioma
  4. Malignant mesothelioma
44
Q

Associated pathology(s): PSA

A

Prostate-specific antigen

1) Prostate CA
2) BPH
3) Prostatitis

45
Q

Associated pathology(s): Prostatic acid phosphatase

A

Prostate carcinoma

46
Q

Associated pathology(s): CEA

A

Carcinoembryonic antigen - very nonspecific. + in ~70% of colorectal and pancreatic cancers. Also in breast and gastric tumors

47
Q

Associated pathology(s): a-Fetoprotein

A

NTDs
Hepatocellular carcinoma
Nonseminomatous germ cell tumor (yolk sac tumor)
DECREASED in Downs Syndrome

48
Q

Associated pathology(s): BhCG

A

Hydatidiform moles
Choriocarcinomas
Gestational trophoblastic tumors

49
Q

Associated pathology(s): CA-125

A

Ovarian Cancer

Malignant epithelial tumors

50
Q

Associated pathology(s): S-100

A

Melanoma
Neural tumors
Astrocytoma

51
Q

Associated pathology(s): Alkaline phosphatase

A

Bone Metastases
Obstructive biliary Disease
Paget’s disease

52
Q

Associated pathology(s): Bombesin

A

Neuroblastoma

Lung and Gastric Cancer

53
Q

Associated pathology(s): TRAP

A

Tartrate-resistant acid phophatase.

Hairy cell leukemia

54
Q

Associated pathology(s): CA-19-9

A

Pancreatic adenocarcinoma

55
Q

Affected Enzyme in Pb poisoning

A

Ferrochelatase and ALA dehydratase

56
Q

Affected Enzyme in acute intermittent porphyria

A

Uroporphyrinogen I Synthase

57
Q

Affected Enzyme in Porphyria cutanea tarda

A

Uroporphyrinogen decarboxylase

58
Q

Accumulated substrate in Pb poisoning

A

Coproporphyrin and ALA

59
Q

Accumulated substrate in acute intermittent porphyria

A

Porphobilinogen and delta-ALA

60
Q

Accumulated substrate in Porphyria cutanea tarda

A

Uropophyrin

61
Q

t(9,22)

A

Philadelphia chromsome - CML (bcr-abl hybrid)

62
Q

t(8,14)

A

Burkitt’s lymphoma (c-myc)

63
Q

t(14,18)

A

Follicular lymphomas (bcl-2)

64
Q

t(15,17)

A

M3 type of AML (responsive to all-trans retinoic acid)

65
Q

t(11,22)

A

Ewing’s sarcoma

66
Q

t(11,14)

A

Mantle cell lymphoma

67
Q

t(8,21)

A

M2 of AML

Pathology (16 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions