Menstural Cycle Flashcards

1
Q

Secondary oocyte is arrested In the which stage

A

Secondary oocyte is arrested In the diplotene stage

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2
Q

Number of follicles is max at

A

Intrauter life 5 th month 6-7 millions
Birth 1-2 million
Puberty 4-5 lakhs follicles

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3
Q

Initial recruitment of follicles is

A

Hormones independent

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4
Q

Gnrh is released in —————- manner

A

Pulsatile

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5
Q

Functions of fsh

A

Prevent follicles from undergoing atresia
Stimulates follicles

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6
Q

Role of fsh

A

Fsh acts on granulosa cells
Estrogen
Inhibit b
Estrogen negative feedback on fsh
Positive feedback on lh
Proliferate uterine endometrium

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7
Q

Fsh receptors are present in

A

Granulosa cells

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8
Q

Granulosa cell tumour of ovary

A

Feminizing tumour because of Estrogen
And inhibit b Is the tumour marker

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9
Q

Inhibit b acts

A

As negative feedback on fsh

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10
Q

Y estroge alone is not given intact uterus patients

A

Endometrial cancer
Endometrial hyperplasia

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11
Q

Role of lh

A

Lh surge
Acts on theca cells
Acts on granulosa cells

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12
Q

Lh surge is initiated by

A

Estrogen

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13
Q

Lh surge

A

Meiosis resumes
Follicles converting into corpus luteum

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14
Q

Estrogen on theca cells

A

Produces androgens

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15
Q

Characteristics is theca cells and granulosa

A

Aromatise enzyme absent
Cyp17

And vice versa

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16
Q

Theca cells receptors for

A

Lh

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17
Q

Granulo cells receptors for

A

Fsh

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18
Q

Role of lh on granulosa cells

A

Acts on granulosa cells
Produces progesterone

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19
Q

Lh receptors preset on

A

Theca and granulosa cells

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20
Q

Protester produced earlier in menstrual cycle

A

32-36 hrs before lh surge

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21
Q

Small quantities of progesterone effects on lh and fsh

A

Positive

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22
Q

Ovarian cycle is initiated by

A

Fsh

23
Q

Size of follicle just before ovulation

A

18 -20 mm

24
Q

Time interval between lh surge and ovulation

A

32 -36 hrs

24 -36 hrs

25
Q

Time inter between lh peak and ovula

A

10 -12 hrs

26
Q

Time between lh peak and Estrogen peak

A

14-24 hrs

27
Q

Lh surge is maintained by

A

Estrogen and progesterone

28
Q

Before ovulation

A

Lh and fsh surge

29
Q

Ovulation is due to

A

Lh surge

30
Q

Meiosis 1 is resumed due to

A

Lh surge 32-36 hrs before

31
Q

First half of cycle is called

A

Follicular phase

Proliferating phase

32
Q

What is cumulus oophorus

A

Granulosa cells surrounding the primary oocyte

33
Q

A trial cavity fluid

A

Estrogen plus growth factor+ lh

34
Q

If lh appears in antral cavity in early phase

A

An ovulation
Occurs in pcos

35
Q

Which hormone maintain corpus leteum

A

Lh

36
Q

Max size attainment by

A

Occurs after 8 days of that is 22 days

37
Q

Hormones produced by the corpus leteum

A

Progesterone
Estrogen
Inhibit a

38
Q

Progesterone action on lh

A

Decrease negative feedback

39
Q

At low concentrations of progesterone

A

Lh positive
Fsh positive

40
Q

High concentration of progesterone

A

Lh negative
Fsh negative

41
Q

Which enzyme is responsible for shedding of endometrium

A

Mettaloprotease enzyme

42
Q

Prostaglandin release in secretary phases

A

PGF 2alpha

43
Q

Oestrogen released on the secretory phase

A

Zona basal is deep layer

44
Q

Second half of cycle is called as

A

Luteal phase
Secretory phase

45
Q

Main hormone I first half of cycle

A

Estrogen

46
Q

Main hormone in second half

A

Progesterone

47
Q

Luteal phase durations vary

A

False fixed for 14 days

48
Q

Which hormone maintains corpus in non pregnant

A

Lh
Pregnant lo hcg

49
Q

Life span of corpus leteum

A

10-12 days
In non pregnancy

In pregnancy
10 -12 weeks
Maintaining by hcg

50
Q

All hormones peak at ovulation

A

Lh fsh Estrogen 24-36 hrs before

51
Q

Progesterone peaks

A

8 days after ovulation

52
Q

Mittelschemerx syndrome

A

Mid cycle abdominal pain

53
Q

Oestrogen is produced. Y

A

Granulosa cells

54
Q

Irregular painless cycles

A

Anovulatory cycles