Gynec Physio Flashcards

1
Q

Kalman syndrome

A

Anosomia and primary amenorrhea

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2
Q

Gnrh is ——— in structure

A

Decapeptide

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3
Q

Gnrh is released from the

A

Paraventricular nucleus of hypothalamus

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4
Q

T1/2 of Gnrh

A

3-4 minutes

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5
Q

Gnrh receptors are

A

Membrane bound receptors

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6
Q

Y Gnrh levels cannot be checked directly in blood due to

A

short half life

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7
Q

Neurons which release gnrh are formed from

A

Olfactory placode

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8
Q

Decreased gnrh leads to

A

Decrease in the lh
Fsh
Estrogen
Progesterone
Primary amenorrhea

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9
Q

Kalyan syndrome is most common in

A

Males
Anosmia and Infertility

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10
Q

Which Norma is best for measuring the gnrh

A

Lh

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11
Q

Hormones that control gnrh

A

Estrogen
Progesterone
Prolactin

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12
Q

Prolactin is secreted by

A

Acidophilc cells of anterior pituitary

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13
Q

Lh and fsh are

A

Peptides

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14
Q

Fsh and lh are secreted by

A

Basophils of anter pituitary

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15
Q

Receptors location of lh is

A

Theca and granulo cells in femLes

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16
Q

Receptors location fsh is

A

Granulosa cells in females
Serotoli cells in the males

17
Q

Lh receptors in males is

A

Leydig cells

18
Q

Functions of fsh

A

Selection of cohort of follicles every month
Selection of dominant follicle
Growth of follicles
Responsible for collagen breakdown at the time of ovulation

19
Q

Function of lh

A

Main hormone responsible for ovulation
Maintenance of corpus leuteum in the non pregnant females

20
Q

Write about Estrogen structure

A

Steroid
C18
Intracellular receptors
Intranuclear receptors
Esterone
Estrsdiol
Estriol
Ee e2 e1e3

21
Q

Naturally occurring Estrogen in reproductive age

A

Estradiol

22
Q

Naturally occurring Estrogen in pose menopausal women

A

Estrone

23
Q

Estrogen specific for pregnancy is

A

E2

24
Q

Estradiol: estrone

A

2:1

25
Q

Estrone mostly comes from the adrenal glands

A

In post menopausal women

26
Q

Hyper Estrogen states

A

Fibroid
Ovarian cancer
Endometrial cancer

27
Q

In obese females excessive androgens will get converted into Estrogen in

A

Adipose tissue

28
Q

Which drug is prescribed in hyper Estrogen if conditions

A

Letrozole

29
Q

How estriol is produced

A

It is produced during pregnancy from placenta
Requiring cheap sulfate for production

30
Q

E2 is produced by the

A

Granulosa cells in the ovary
Corpus leuteum