Gynec Pharma Flashcards

1
Q

Recombinant lh

A

Leutropin alpha

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2
Q

Recombinant hcg

A

Choriogonadotropin alpha

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3
Q

What is the disadvantage of recombinant fsh lh hcg

A

Expensive

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4
Q

Recombinant fsh

A

Folliotropin alpha beta delta

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5
Q

Patients who have both lh and fsh deficiency

A

Hmg is preferred

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6
Q

Synthetic steroidal Estrogen

A

Ethynyl Estradiol
Micronised 17 beta Estradiol
Conjugated equine Estrogen

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7
Q

Synthetic non steroidal derivatives

A

Di ethyl stillbestrol
Di enesterol

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8
Q

Teratogenic Estrogen

A

Diethylstillbestrol fetal malformations

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9
Q

In male fetus lo what does diethylstillbestrol do

A

Renal anomalies
Cryptorchidism,

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10
Q

In female fetus effect of diethyl sterbestrol

A

Clear cell carcinoma of vagina
Cervix hypoplastic uterus t shaped uterus

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11
Q

Lowest possible dose ofethynyl Estradiol which causes contraceptive effect

A

10mu g

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12
Q

High dose pills

A

Ee > 50microgm

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13
Q

Low dose pills lo <

A

35-50 microgm

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14
Q

Conjugate equine Estrogen is derived from

A

Urine of pregnant mares mainly e1

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15
Q

0.625 mg of conjugated equine Estrogen is equals to

A

1 mg of micronised 17 beta Estradiol
5mcg of ee
O.o5 mg of transdermal estradiol

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16
Q

Uses of Estrogen

A

Non contraceptive uses of ocps
Atypically uterine bleeding
Hormone replacement therapy
In hot flushes
Genitourinary symptoms like dry vagina that occur due to th scanty. Revival mucous production
Osteoporosis

Contraception

17
Q

How thrombo embolism venous is caused due to excess Estrogen

A

Due to high first pass metabolism
In the veins the Estrogen content increases
That increases
Sex hormone binding globulin
Increased clotting factors
Triglycerides
Hdl

18
Q

Through which route venous thromboembolism

A

Transdermal Estrogen
Less effect on serum lipid concentration

19
Q

What is the preferred method of route for Estrogen

A

Transdermal route

20
Q

In which conditions topical vaginal Estrogen is given

A

Genitourinary sympt like dyspareunia,senile vaginitis in the post menopausal femlaes

21
Q

Main. Hormone involved in the anovulation is

A

Fsh

22
Q

Doc for irregular cycles

A

Ocps

23
Q

What is used in the bone osteoporosis

A

Raloxefene