Gynec Pharma Flashcards
Recombinant lh
Leutropin alpha
Recombinant hcg
Choriogonadotropin alpha
What is the disadvantage of recombinant fsh lh hcg
Expensive
Recombinant fsh
Folliotropin alpha beta delta
Patients who have both lh and fsh deficiency
Hmg is preferred
Synthetic steroidal Estrogen
Ethynyl Estradiol
Micronised 17 beta Estradiol
Conjugated equine Estrogen
Synthetic non steroidal derivatives
Di ethyl stillbestrol
Di enesterol
Teratogenic Estrogen
Diethylstillbestrol fetal malformations
In male fetus lo what does diethylstillbestrol do
Renal anomalies
Cryptorchidism,
In female fetus effect of diethyl sterbestrol
Clear cell carcinoma of vagina
Cervix hypoplastic uterus t shaped uterus
Lowest possible dose ofethynyl Estradiol which causes contraceptive effect
10mu g
High dose pills
Ee > 50microgm
Low dose pills lo <
35-50 microgm
Conjugate equine Estrogen is derived from
Urine of pregnant mares mainly e1
0.625 mg of conjugated equine Estrogen is equals to
1 mg of micronised 17 beta Estradiol
5mcg of ee
O.o5 mg of transdermal estradiol
Uses of Estrogen
Non contraceptive uses of ocps
Atypically uterine bleeding
Hormone replacement therapy
In hot flushes
Genitourinary symptoms like dry vagina that occur due to th scanty. Revival mucous production
Osteoporosis
Contraception
How thrombo embolism venous is caused due to excess Estrogen
Due to high first pass metabolism
In the veins the Estrogen content increases
That increases
Sex hormone binding globulin
Increased clotting factors
Triglycerides
Hdl
Through which route venous thromboembolism
Transdermal Estrogen
Less effect on serum lipid concentration
What is the preferred method of route for Estrogen
Transdermal route
In which conditions topical vaginal Estrogen is given
Genitourinary sympt like dyspareunia,senile vaginitis in the post menopausal femlaes
Main. Hormone involved in the anovulation is
Fsh
Doc for irregular cycles
Ocps
What is used in the bone osteoporosis
Raloxefene