Menopause Flashcards
Menopause is the result of permanent loss of
estrogen.
The average age of menopause in the United States is
51
The oocytes produce less _____, and both the ____
start to rise
estrogen and progesterone
LH and FSH
Women are symptomatic for an average of___ but ___
12 months, but some
women can experience symptoms for years.
Symptoms
Menstrual irregularity
Sweats and hot flashes
Mood changes
Dyspareunia (pain during sexual intercourse)
Physical Exam Findings
Atrophic vaginitis
Decrease in breast size
Vaginal and cervical atrophy
The diagnosis is based on
clinical presentation
If the diagnosis is unclear, do this test
FSH level=increased
short-term symptomatic relief Tx
Hormone replacement therapy (HRT)
______can be used to treat symptoms of depression and some are also effective for vasomotor symptoms.
SSRIs
complementary management
prevention of
osteoporosis.
Vaginal atrophy and dyspareunia can be treated with
topical estrogen cream.
Dyspareunia can also be treated with
prasterone, a dehydroepiandrosterone
(DHEA) analogue with weak androgenic and weak estrogenic activity.
when to choose prasterone
May be preferred if it is beneficial to have weaker estrogen exposure.
HRT is associated with ____ and can lead to ___. For this reason, HRT use is limited to ___
endometrial hyperplasia
endometrial carcinoma
5 years.
