Meningocccal Disease (and meningococaal septicaemia)

Question 1

what is meningococcus?

Answer 1

bacteria

Question 2

meningococcus aka?

Answer 2

Neisseria meningitidis

Question 3

if infected by meningococcus, what is the disease called?

Answer 3

Meningococcal Disease

Question 4

if meningococcus infection causes meningitis, what is the disease called now?

skin feature of this?

Answer 4

meningococcal meningitis

non-blanching rash

Question 5

if meningococcus infection goes into blood, what is the disease called now?

skin feature of this?

Answer 5

meningococcal septicaemia

petechiae

Question 6

Vaccines against meningococcus are called what?
-2

what bacterial strain does each vaccine protect against?

Answer 6

Men C for meningococcal C

meningitis B for meningococcal B

Question 7

child with meningococcal septicaemia,
BP suddenly drops,

what is this called now?

Answer 7

decompensated sepsis

Question 8

why is petechiae made in meningococcal septicaemia?

Answer 8

Neisseria meningitidis gets into blood > releases endotoxins > causes DIC, disseminated intravascular coagulation > thrombi made block BVs causing ischaemic damage + thrombi use up clotting factors so you haemorrhage easily > toxins from ischaemia breaks down very capillary walls & you have no clotting factors so > bleed into the skin > makes petechiae + Blood volume falls

Question 9

when lots of petechiae coalesce, what is this called?

Answer 9

purpura

Question 10

if Capillaries leak blood into space, what dangerous complication can happen?
(this is rare and only in severe cases)

Answer 10

compartment syndrome

Question 11

Capillaries leak into lungs space as well,
what complication now happens?

if very SOB and child can not breathe what mainstay Mx will you have to do ?

Answer 11

pulmonary oedema

ventilation

Question 12

what happens to capillary walls in meningococcal septicaemia?

Answer 12

break down > bleed

Question 13

if capillary walls bleeding what happens to BV?

risk of this?

Answer 13

lowers

easier to go into decompensated shock (sepsis)

Question 14

if capillary walls bleeding what happens to BV?

risk of this?

how will you treat above?
-2 things ( one is drug class)

Answer 14

lowers

easier to go into decompensated shock (sepsis) - ↓↓↓BP

lots of fluids and inotropes

Question 15

when Managing Septicaemia what do you do first?

Answer 15

sepsis 6

Question 16

child has meningococcal septicaemia, with ↓↓↓BP.

how do you treat?
-2 things ( one is drug class)

Answer 16

lots of fluids and inotropes

Question 17

child has meningococcal septicaemia.

how do you treat infection itself?
drug group

Answer 17

Antibiotics

Question 18

child has meningococcal septicaemia, gets pulmonary oedema and SOB.

mainstay treatment for this now?
-2

Answer 18

intubation + ventilation

Question 19

child has meningococcal septicaemia, low BV has caused kidney failure.

how do you treat this?

Answer 19

Dialysis

Question 20

when petechiae go into recover phase what colour does it become?

Answer 20

brown

Question 21

is brown petechiae a good or bad sign?

Answer 21

good

Question 22

petechiae coalesce into what?

Answer 22

purpura

Question 23

when purpura gets worse it is called what?

Answer 23

echymosis

Question 24

child has meningococcal septicaemia?

Initial Symptoms of Meningococcal septicaemia?
-9

Answer 24

fever
nausea
myalgia
headache
arthralgia
chills
diarrhoea
stiff neck
malaise

Question 25

child has meningococcal septicaemia,

infection worsens, goes into compensated shock, signs of this?
-5

Answer 25

petechiae
pale and cold
low CR
tachycardic
lose tone

Question 26

child has meningococcal septicaemia,

infection gets really bad, goes into decompensated shock, main sign of this?
-1

Answer 26

very low BP