Meninges + Vascular Supply Flashcards
meninges
three layers of membrane surrounding the brain and spinal cord
layers of the meninges
dura mater
arachnoid mater
pia mater
functions of the meninges
- dura - protection from mechanical injury
- arachnoid - provide space for flow of CSF
- pia - provide blood supply to the skull and cerebral hemispheres
dura mater
outermost, thick membrane composed of two layers
- contains fibroelastic cells
- highly vascularized
- innervated by CN V
PERMEABLE: abundant collagen, no tight junctions
functions of the dura mater
- cover/protect brain and spinal cord
- regulate neural progenitor migration/generation
- limit rotational displacement of the brain
- regulate glial cells
- regulate axon behavior at CNS/PNS interface
layers of the dura
- periosteal layer
- meningeal layer
periosteal layer
superficial; closest to calvarium
meningeal layer
inner layer; closest to CNS parenchyma, contains larger blood vessels
dural reflections
folds in the dura that limit rotational displacement of the brain
- falx cerebri/cerebelli: divides hemispheres
- tentorium cerebelli: separates cerebrum/cerebellum
arachnoid mater
middle membrane composed of crossing fibers that connect to the pia mater
- IMPERMEABLE: little collagen, has tight junctions
functions of the arachnoid
house the arachnoid space (subarachnoid space) for flow of CSF
arachnoid membrane
thin, fibrous tissue formed by flat cells that prevent diffusion of CSF
arachnoid trabeculae
strands of connective tissue that loosely join the arachnoid barrier cells with the pia mater
subarachnoid space
space within the arachnoid mater filled with CSF
arachnoid villi/granulations
protrusions of arachnoid membrane that cross the dura into the venous sinuses that allow CSF to be reabsorbed into circulation
- maintains UNIDIRECTIONAL flow of CSF
ways to maintain unidirectional flow of CSF from SAS –> venous sinus –> circulation
pressure differences; flows from high to low
subarachnoid space: high pressure
venous sinuses: low pressure
arachnoid cisternae
widest portions of subarachnoid space used to collect CSF
cisterna magna
clinically important arachnoid cisterna for CSF taps; located at the junction of the atlas and the occipital lobes
pia mater
thin, mesh membrane that tightly follows the brain and spinal cord
- follows all gyri/sulci
- interlaced with blood vessels that are important for vascularization of CNS