ANS Main Drugs Flashcards
norepinephrine
(a1, b1 agonist)
increase HR/contractility (transient)
vasoconstriction & hypertension
decreased femoral blood flow
increased resistance
epinephrine
(B1, B2, a agonist)
increase HR/contractility (long term)
vasoconstriction & hypertension
increased femoral blood flow
isoproterenol
(B1, B2 agonist)
increase HR/contractility (long term)
vasodilation –> hypotension
increased femoral blood flow
decreased resistance
albuterol
(B2 agonist)
bronchodilation
vasodilation
acepromazine
(D2/a1 antagonist)
D2 antagonist:
antiemetic
reduced anxiety/fear
a1 antagonist:
sedation
vasodilation & hypotension
decreased HCT
dexmedetomidine
xylazine
(a2 agonist)
sedation
analgesia
amnesia
muscle relaxation
bradycardia
high dose: vasoconstriction & hypertension
low dose: vasodilation & hypotension
inhibit ADH –> increase urination
inhibit insulin –> hyperglycemia
acetylcholine
(N/M agonist)
decreased HR/contractility
bronchoconstriction
miosis
skeletal muscle contraction
atropine
jimsonweed
(muscarinic antagonist)
increased HR/contractility
mydriasis
bronchodilation –> resp paralysis
decrease secretions –> dry mouth/thirst
urine retention
fever
organophosphate pesticides (AChE inhibitor)
DUMBELS
diarrhea
urination
miosis
bronchospasm (constriction)
emesis
lacrimation
salivation
muscarine
(muscarinic agonist)
bronchospasm (constriction)
diarrhea
miosis
urination
excess secretions
nicotine
(nicotinic agonist)
vomiting
tremors and muscle weakness
ataxia
increased HR/contractility
respiratory distress (tachypnea)
hypertension
mydriasis
death
morphine
(u/k opioid agonist)
analgesia
sedation
hypoventilation
decreased peristalsis
midazolam
(benzodiazepine)
sedation/excitement (spp.)
anticonvulsant
amnesia
decreased muscle tone
propofol
(anesthetic GABAa)
anesthesia
sedation/excitement (spp.)
anticonvulsant
decreased muscle tone
hypoventilation
ketamine
(NMDA antagonist)
hallucinations
dissociative anesthesia
amnesia
analgesia
increased tone/rigidity
spontaneous movement
