Mendelian Inheritance

Question 1

What shape are sickle cell anaemia cells?

Answer 1

Sickle-shaped (more curved that regular red blood cells)

Question 2

What can sickle cell anaemia cause in the body?

Answer 2

Tissue damage, pain, infection and even death (includes jaundice, stroke, leg ulcers, affected kidneys)

Question 3

What disease are sickle cell sufferers are immune to?

Answer 3

Malaria

Question 4

What sort of genetic condition is sickle cell anaemia?

Answer 4

Autosomal recessive disorder (not sex linked)

Question 5

In recessive disorders, if both mother and father are carriers, what is the ratio of each child being affected, not affected and carrier?

Answer 5

1 affected, 1 unaffected and 2 carriers

Question 6

In a recessive disorder, if the father is a carrier and a mother is a non-carrier, what is the ratio of each child being affected, not affected and a carrier?

Answer 6

2 carriers and 2 non-carriers

Question 7

What are the main symptoms affected by cystic fibrosis?

Answer 7

sinuses, lungs, skin, liver, pancreas, reproductive organs and intestines

Question 8

What does cystic fibrosis cause to the airway of the sufferer?

Answer 8

Thick mucus blocks airways, blood found in mucus and bacterial infection can develop in airway

Question 9

What sort of genetic condition is cystic fibrosis?

Answer 9

Autosomal recessive

Question 10

What is a common example of a common autosomal dominant genetic condition?

Answer 10

Achondroplasia

Question 11

In a dominant disorder, if the father is affected and the mother is not affected, what is the ratio of children being affected and not affected?

Answer 11

2 affected and 2 not affected