Mendelian Inheritance Flashcards

1
Q

The “Father” of Genetics

A

Gregor Mendel

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2
Q

Who was Mendel?

A

Monk
Later an Abbot after his work was ignored by the scientific community
Beekeeper
Meterologists
Physicists
Biologist
Mathematician
Theologian
Most of the work between 1853-1856
Breeding experiments took several years just to get enough homozygous plants in order to breed

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3
Q

What is the The Chromosomal Theory of Inheritance?

A

The chromosomal theory of inheritance is the idea that genes, the units of heredity, are physical in the chromosomes
Chromosome are seen in all dividing cells and are passed from generation to generation

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4
Q

How are Chromosomes Arranged

A

One homologous of any pair is derived from one parent and its partner from the other parent

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5
Q

How many pairs of autosomal chromosomes are in the human genome??

A

22

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6
Q

How many pairs of sex chromosomes are there?

A

1

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7
Q

Chromosomal number of a Garden Pea

A

2n 14
n=7

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8
Q

Define Genes

A

Unit of DNA that transmits genetic information. Codes for a specific protein that will play a structural of functional role in the sell

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9
Q

Define Genotypes

A

sets of alleles that are present for the type.

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10
Q

Define phenotypes

A

Observable physical traits produced by the actions of one or more gene-encoded proteins

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11
Q

How is the F2- Second filial generation obtained?

A

obtained by inbreeding the F1 generation

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12
Q

What forms Alleles:

A

Mutation
The formation of different alleles is due to errors in DNA replication and can occur in mitosis or meiosis
Can be passed on if it occurs in a germ cell
Usually result in some sort of altered protein
Usually not lethal

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13
Q

Define recessive

A

the trait not expressed where the dominant form of the trait is present

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14
Q

Define dominant

A

the expressed form of the trait when present ( even if it just 1 allele)

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15
Q

Homozygous

A

both alleles are identifical

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16
Q

Heterozygous

A

two different alleles are non-identical

17
Q

What are Mendel’s ratios:

A

3:1

18
Q

What is Laws of Dominance

A

F1 generation always showed the dominant trait

19
Q

What is a Monohybrid crosses

A

Mating two of any individual with a variant in any one trait
F2- 3:1 ratio

20
Q

What’s Mendel’s Recurring Ratios

A

F2 generation ratio was consistent

21
Q

What’s Dihybrid

A

looks at two traits at one time
Ratio 9:3:3:1

22
Q

What is Segregation

A

During meiosis, alleles segregate
Homologous chromosomes separate
Each allele for a trait is packaged into a separate gamete

23
Q

What is Independent Assortment

A

Alleles for 1 trait sort into gametes independently of the alleles for a 2nd trait

24
Q

Who is credited with first proposing the chrome theory of inheritance

A

Walter Sutton

25
Q

What is Gene Linkage

A

is the tendency of alleles that ae close together on a chromosome to be inherited together during the meiosis phase of sexual reproduction
Violates Mendel’s law of independent assortment

26
Q

_________ violates Mendel’s law on dominance

A

Incomplete dominance

27
Q

_________occurs when both characteristics are expressed

A

Codominance

28
Q

What is Pleitrophy

A

one allele can have an effect on more than one trait
eg Sickle Cell Anemia

29
Q

What is Epistasis

A

One allele can influence the expression of a different allele