Mendelian Genetics Flashcards

1
Q

Gregor Mendel

A
  • the father of genetics
  • monk who lived 1822-1884
  • from Austrian Empire (Czech’s Republic)
  • crossed pea plants
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2
Q

Pea Plants

A
  • organisms that mendel used in his studies
  • pea plants have both female and male parts, and he would use those different parts to experiment with genetics.
  • pea plants can cross and self pollinate
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3
Q

P, F1, and F2 generation

A

P = parent generation
F1 = first generation
F2 = second generation

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4
Q

Genes

A

units that contain and determine the heredity information of an organism

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5
Q

Alleles

A

the varying form of a gene: one from mother and one from fathe

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6
Q

Dominant

A

the main trait that appears in an organism’s offspring

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7
Q

Recessive

A

the hidden trait that is not expressed by an organism’s offspring

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8
Q

Testcross

A
  • crossing an individual of dominant phenotype but unknown genotype with a homozygous recessive individual to determine the genotype of the dominant individual
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9
Q

True (Pure) Breeding

A
  • a cell that can only produce one type of allele
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10
Q

Homozygous Dominant

A

Two dominant alleles

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11
Q

Homozygous Recessive

A

two recessive alleles

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12
Q

Heterozygous

A
  • two different alleles
    (one dominant allele and one recessive
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13
Q

Genotype

A
  • the specific alleles an organism has for a particular trait
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14
Q

Phenotype

A
  • a trait that is visibly displayed
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15
Q

Monohybrid Crosses

A
  • a single trait with two alleles
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16
Q

Dihybrid Crosses

A
  • two traits
  • each trait has two alleles
  • the phenotypic ratio of two heterozygous individuals in a dihybrid cross is 9:3:3:1
17
Q

Codominance

spotted

A
  • two alleles
  • neither allele is dominant over the other allele
  • both alleles are expressed

*like blood type AB or a flower with multiple colors.

18
Q

Incomplete Dominance

mixed

A
  • two alleles
  • neither alleles is dominant over the other
  • a phenotype is a blend of the two alleles

*black plus white = grey

19
Q

Multiple Alleles

A
  • one trait, but more than two alleles
20
Q

Blood Types

A

i = immunoglobulins (antibody)
ii = O blood type
AA or Ai = A blood type
BB or Bi = B blood type
AB = AB blood type

21
Q

Universal Donor?
Universal Recipient?

A

O is the universal donor
AB is the universal recipient

22
Q

Antigens

A
  • on the red blood cells
  • native to your body
  • anitgens allow your body to create a defense against future invaders
23
Q

Antibodies

A
  • defense protein that is part of the immune system
  • found in the plasma
  • blood antigens are carbohydrate sugars
  • O and B blood carry anti-a antibodies
  • O and A carry anti-b antiobodies
  • AB does not carry any antibodies
24
Q

Rh+ and Rh-

A
  • whether someone has a positive or negative blood type
  • this determines wherter someone can recieve a certain type of blood.
  • if Rh+ blood gets into the negative bloodstream the body will consider those cells to be foreign invaders and will create antibodies to destroy them.
  • someone with Rh+ can recieve both Rh+ and Rh-
25
Rh incompatiblity during pregnancy?
- if the mother has rH- and the baby is rH+ - the first baby can be carried full term because the body does not have enough time to react to the antigens. any babies born after are at risk.
26
Drosophila Melanogaster | fruit fly duhh
- genus = drosophila - melanogaster = species - 4 pairs of chromosomes - 3 pairs of autosomes - 8 chromosomes in total
27
Tay-Sachs | autosomal recessive
- chromosome 15 - defensize enzyme prevents lipid breakdown in neurons, leading to vegatative state and death in childhood - Ashkenazi Jewish
28
Sickle Cell Anemia | autosomal recessive
- chromosome 11 - defective hemoglobin leads to sickle shaped RBCs - Africans and sickle cell remains in this population because it protects Africans against malaria.
29
Cystic Fibrosis | autosomal recessive
- chromosome 7 - lung problems, sticky mucous - (Australian, Northern European, French Canadian)
30
Huntingtons | autosomal dominant
- a problem in the nervous system that affects concentration, mood, and overall nervous system.
31
Marfans | autosomal dominant
- a genetic disorder that changes the proteins that help make healthy tissues. - cardiovascular, eye, and skeletal complications.
32
Polydactyly | autosomal dominant
- extra finger or toe
33
Colorblindness | sex-linked recessive
- specifically red-green color blindness - a person cannot distinguish shades of red and green
34
Hemophilia | sex-linked recessive
- an inherited blood disorder in which the blood does not clot properly.
35
Duchenne Muscular Dystropy | sex-linked recessive
- progressive muscle degeneration and weakness