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Pharm Drug -- Exam 2 > Men's Health Drugs > Flashcards

Men's Health Drugs Flashcards

1
Q

What is Endogenous testosterone used for>

A

Testosterone deficiency

Hypogonadism

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2
Q

What are the 2 biggest adverse effects of Endogenous testosterone?

A

Virilization

Hepatotoxicity

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3
Q

What is Methyltestosterone used for?

A

Delayed puberty

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4
Q

what are the 5 drugs used for Erectile dysfunction?

A 
Sildenafil
Vardenafil
Tadalafil
Avanafil
Alprostafil
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5
Q

what side effect can Erectile dysfunction drugs lead to?

A

hypotenstion due to vasodilation

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6
Q

What do you want to try to do to decrease premature ejaculation ? (pharmocologically)

A

decrease serotonin uptake –> basically shit you give for depression

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7
Q

What is Finasteride used for?

A

BPH

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8
Q

What is Dutasteride used for?

A

BPH

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9
Q

What kind of obstruction do Finasteride & Dutasteride produce

A

MECHANICAL OBSTRUCTION

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10
Q

How does Finasteride & Dutasteride work?

A

Promotes regression of epithelial tissue = decreased mechanical obstruction

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11
Q

What is Silodosin used for?

A

BPH

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12
Q

What is Tamsulosin used for?

A

BPH

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13
Q

What kind of obstruction do Silodosin & Tamsulosin produce

A

DYNAMIC OBSTRUCTION

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14
Q

how does Silodosin & Tamsulosin work?

A

Relaxes smooth muscle in bladder neck, prostate capsule = decreased dynamic obstruction

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15
Q

Hypotension is likely due to the combination sildenafil and _______ are taken together?

A

nitroglycerin sublingual

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16
Q

What are pathophysiologic difference between mechanical obstruction vs. dynamic obstruction of the urethra in BPH

A

Mechanical obstruction has to do with epithelial obstructing the urethra

Dynamic obstruction has to do with smooth muscle obstruction urethra

17
Q

An absolute contradiction of sildenafil

A

Vasodilators

18
Q

which androgens are hepatotoxic?

A

Any 17-alpha-alkylated compounds (Methyltestosterone, Oxandrolone, Oxymetholone, Stanozolol)

Pharm Drug -- Exam 2 (10 decks)

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