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Pharm Drug -- Exam 2 > Drugs for diabetes > Flashcards

Drugs for diabetes Flashcards

1
Q

Types of Rapid short acting insulin

A

Lispro
Aspart
Glulisine

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2
Q

What is the onset and duration of Rapid short acting insulin

A 
Onset = 15-30mins
Duration = 0-4 hours
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3
Q

When should Rapid short duration insulin be given

A

during meal time

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4
Q

Types of regular short acting insulin

A

Humulin R

Novolin R

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5
Q

What is the onset and duration of Regular short acting insulin ?

A 
Onset = 30-60mins 
Duration =  5-8  hours
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6
Q

How soon should you give Regular short acting insulin before a meal?

A

30 mins before meal

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7
Q

Types of Intermediate Duration insulin

A

Humulin- N

Novolin - N

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8
Q

What is the onset and duration of Intermediate Duration insulin

A 
Onset = 2-4 hours
Duration= 10-18
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9
Q

Types of Long acting insulin

A

Lantus

Glargine

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10
Q

What is the onset and duration of Long acting insulin

A 
Onset= 2-4 hours
Duration= 24 hours
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11
Q

What insulin do you NEVER mix?

A

Lantus

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12
Q

What does Metformin do?

A

Inhibits liver glucose production

Sensitizes insulin receptors

Reduces gut glucose absorption

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13
Q

What vitamin absorption can be impacted when taking Metformin

A

B12 & folate absorption

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14
Q

what does Glipizide & Glyburide do?

A

Promotes insulin release

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15
Q

what does Nateglinide & Repaglinide do?

A

Promotes insulin release

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16
Q

What is Pioglitazone & Rosiglitazone used for?

A

to increase insulin efficacy

17
Q

Use Pioglitazone & Rosiglitazone with caution with….

A

Heart failure due to fluid retention

18
Q

what does Acarbose & Miglitol do?

A

Decrease absorption of carbs from GI tract = decreased the postprandial rise

19
Q

long term effecs of Acarbose & Miglitol

A

liver dysfunction

20
Q

what does dipeptidyl peptidase-4 (DDP-4) inhibitors do>

A

Increase glucose-dependent insulin release

Decrease glucagon release

21
Q

what does sodium-glucose cotransporter-2 (SGLT-2) inhibitors do?

A

Increase glucose-dependent insulin release
Decrease glucagon release
Helps reabsorb glucose in the kidneys

22
Q

what is glucagon used for?

A

Hypoglycemia

23
Q

what does glucagon do?

A

Stimulates liver glucose production

24
Q

what does Mylin mimetic do?

A

Delayed gastric emptying, suppression of glucagon → Results in the decreased postprandial rise of glucose

25
Q

Which insulin would be used in a placement pump to have tight control?

A

Lispro

26
Q

Which two oral antidiabetics have a hypoglycemia risk?

A

glipizide & repaglinide

Pharm Drug -- Exam 2 (10 decks)

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