MEN Flashcards
1
Q
MEN1 (Wermer’s syndrome)
Characteristic
A
Parathyroid tumors Pituitary tumors (prolactin or GH) Pancreatic endocrine: zollinger-ellison, insulinoma, VIPoma, glucagonomas (rare)
2
Q
MEN1 (Wermer’s syndrome)
Presentation
A
Commonly with kidney stones and stomach ulcers
3
Q
Zollinger Ellison
A
Gastin secreting tumor of pancreas or duodenum
Stomach shows rugal thickening with acid hyper secretion
Recurrent ulcers
Associated with MEN1
4
Q
MEN 2A (sipple syndrome)
A
Medullary thyroid carcinoma
Pheno
Parathyroid
5
Q
MEN 2B
A
Medullary thyroid carcinoma
Pheo
Oral/intestinal ganglioneuromatosis (associated with marfanoid habitus)
6
Q
How to remember
A
MEN1: diamond
MEN2A: square
MEn3A: triangle
7
Q
All MEN syndrome
A
Autosomal dominant
MEN 2A/B: ret gene mutation.