Membranes and Cells Flashcards
what is the fluid mosaic model
the general structure of membranes
T or F: proteins float on the phospholipid bilayer
T
what part of the phospholipid is hydrophilic
the head
what part of the phospholipid is hydrophobic
the tail
why do lipids maintain a. bilayer organization spontaneously
helps membranes fuse during exocytosis
what is a phospholipid structure called in the cell
a vesicle
can membranes vary in lipid composition
yes
how do phospholipids vary
fatty acid, chain length, degree of saturation, phosphate head groups
what is the structure of the phospholipid bilayer
flexible and the interior is fluid allowing lateral movement of molecules
what does fluidity depend on
temperature and lipid composition
higher temp = more fluid
lower temp = less fluid
how to the phospholipid tail lengths affect fluidity
shorter tail = more fluid
longer tail = less fluid
what is the fluidity of saturated vs unsaturated fatty acids
saturated = less fluid (no double bonds)
unsaturated = more fluid (one or more double bonds)
where are the carbohydrates on the membrane
outer surface
what purpose to carbohydrates serve on the outer surface of the membrane
recognition sites for other cells and molecules
what type of protein is typically a transmembrane protein: span the bilayer, hydrophilic ends protrude on either sides
integral membrane protein
what type of membranes do not penetrate the bilayer and are only temporarily associated with the internal or external side of the membrane
peripheral membrane proteins
T or F: some membrane proteins can move freely within the bilayer, while some are anchored to a specific region
T
what are membrane proteins anchored by
cytoskeleton or lipid rafts (a defined patch of membrane with distinct components
FRAP experiment
used mouse cells to prove that membrane proteins can diffuse rapidly in the plane of a membrane
what is selective permeability
some substances can pass through, but not others (membranes have this)
what is passive transport
no outside energy required - diffusion based
what are the two types of passive transport
- simple diffusion
- facilitated diffusion
what is active transport
movement of substances across the membrane AGAINST a concentration and/ or electrical gradient and it REQUIRES ENERGY
what are the two types of active transport
- primary active transport
- secondary active transport
what is the NET movement from regions of greater concentration to regions of lesser concentration
diffusion
what is it called when particles continue to move, but there is no net change in distribution
equilibrium
what does diffusion rate depend on
diameter of molecules (larger = slower)
temperature of solution (higher temp = faster)
electrical charges (like charges repel = slow and opposite charges attract = faster)
concentration gradient (big difference = rate higher)
what is permeable
solutes move easily though membrane
what is impermeable
solutes cannot move across membrane
what type of diffusion: hydrophobic molecules easily pass through the lipid bilayer
simple diffusion