cytoskeleton Flashcards

1
Q

_______ are important players in signaling pathways and they phosphorylate other proteins

A

kinases

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2
Q

_______ can induce a change in protein structure and this modulates protein activity by either activation or inactivation

A

Phosphorylation

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3
Q

what are the three components of the cytoskeleton

A

microfilaments
intermediate filaments
microtubules

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4
Q

what are the functions of the cytoskelton

A

cell shape
cell movement
“cargo” transport
cell division
and muscle contraction

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5
Q

which cytoskeleton have globular monomer

A

microtubules and microfilaments

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6
Q

which cytoskeleton have flimentis monomer

A

intermediate filaments

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7
Q

form a rigid internal skeleton in some cells
act as tracks for motor proteins
form the miotic spindle
POLAR
MADE OF TUBULIN

A

microtubules

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8
Q

what are the microtubule based structures that protrude from the membrane (can be used to move cells)

A

cilia and flagella

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9
Q

what is the array that microtubules are assembles in

A

9+2 array

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10
Q

what are part of the centrism and made of microtubules
(NOT IN PLANTS)

A

centrioles

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11
Q

made from ACTIN
required for cell movement
determine cell shape
also tracks for motor proteins
central to MUSCLE contractions
required for cytokensis
POLAR

A

microfilaments

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12
Q

what is inside microvilli

A

actin microfilaments

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13
Q

fibrous proteins coiled into thicker cables
KERATIN is an example found in epithelial cells
stabilize cell structure and resist tension
overall NONPOLAR structure
NOT IN PLANTS

A

intermediate filaments

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14
Q

a mass of cells dividing in an uncontrolled manner

A

tumor

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15
Q

the spread of tumor cells to other parts of the body (usually a problem)

A

metastasis

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16
Q

what do doctors often use ________ proteins as indicators of metastasis

A

intermediate filamants

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17
Q

the ______ nature of microtubules and microfilaments allows for ____________________

A

dynamic
vacation in cell shape

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18
Q

microtubule dynamic stability allows microtubules to

A

space the cell and find chromosomes to attach to

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19
Q

actin and tubular proteins are highly _______ between different eukaryotic organisms

20
Q

what are the three types of movement associated with cells

A
  1. shape change
  2. movement of organelles or molecules inside the cell
  3. cell mmigrations
21
Q

__________ undergo reversible shape changes powered by ATP

A

motor proteins

22
Q

what associates with microfilaments or microtubules to create movement

A

motor proteins

23
Q

_________ binds to actin filaments causing the filaments to slide relative to one another

24
Q

_______ moves cargo toward the minus end of the microtubule

25
______ moves cargo toward the plus end
kinesin
26
_______ activity moves the cilia
dynein
27
what are the two approaches cell biologists use to show cause and effect
chemical inhibition genetic mutation
28
a collection of cells that work together to perform a specific function
tissue
29
what are the four types of tissue
epithelial connective nervous muscle
30
a collection of tissues joined in a structural unit to serve a common function
organ
31
a _______________ is reflected in its shape and internal structure
cells function
32
cells arrange themselves in groups by __________
cell adhesion
33
cell surface proteins mediating cell attachment to other cells or the ECM
cell adhesion molecules
34
specialized structures on the plasma membrane where cells adhere to other cells and the ECM
cell junction
35
what cell adhesion molecules bind cells to one another
cadherins
36
what cell adhesion molecules bind to the ECM
integrins
37
what are the three main types of cell junctions holding animal epithelial cells together
adherens junction desmosomes tight junction
38
what junctions connect adjacent epithelial cells (made with cadherins) and are anchored to actin microfilaments
adherens junctions
39
what junction connect adjacent epithelial cells (made with cadherins) and are anchored to intermediate microfilaments
desmosomes
40
what type of junction ensure the directional movement of material (not made with cadherins) and are connected to actin microfilament
tight junction
41
what type of junction link cells to the ECM (made of integrins) and anchored to the cytoskeleton IF
hemidesmosome
42
what type of junction allow communication between cells (made of cadherins) form channels connecting the cytoplasm of adjacent cells
gap junctions
43
what connects the cytoplasms of plant cells
plasmodesmata
44
is the plasma of the cell membrane continuous
yes
45
________ opening than gap junction allows _______ to pass through
larger proteins