Membranes Flashcards
What is compartmentalisation?
Separation of organelles and areas of cells via membranes
What is the plasma membrane?
A basic structure that separates the cell from its external environment
What is the phospholipid bilayer?
Hydrophilic phosphate group heads and hydrophobic fatty acid tails that form the plasma membrane
What is the fluid mosaic model?
A model presented of plasma membranes that shows proteins incorporated intrinsically and extrinsically
What are membrane proteins?
Proteins in the plasma membrane that are either intrinsic and extrinsic
What are intrinsic proteins?
Proteins that are embedded through both layers of the plasma membrane and come in two types; carrier and channel
What are channel proteins?
Proteins that have a hydrophilic channel and allow passive movement for polar molecules and ions
What are carrier proteins?
Proteins that have a role in passive and active transport and often changes the shape of the protein
What are glycoproteins?
Intrinsic proteins embedded with carbohydrate chains with varying lengths and sizes, they play a role in adhesion and cell signaling (neurotransmitters, peptide hormones (insulin, glucagon))
What is cell signaling?
When a chemical binds and elicits a cascade response inside the cell
What are glycolipids?
Extrinsic lipids with attached carbohydrate chains that act as cell markers and antigens
What are extrinsic proteins?
Proteins that are on one side of the plasma membrane
What are the roles of the plasma membrane?
Environment, transport, cell to cell signaling, detecting changes in the environment, site of chemical changes, pseudopodia, anchorage for the cytoskeleton, cell to cell joining
How does the plasma membrane effect the environment?
Maintains a fixed set of conditions inside the cell
How does the plasma membrane effect transport?
Provides a partially permeable membrane to control which substances enter and exit the cell
How does the plasma membrane effect cell to cell signaling?
Have either glycoproteins or lipoproteins to interact between cells
How does the plasma membrane effect detection of environment changes?
Signal transduction- so having proteins that can act as receptors for hormones
How does the plasma membrane effect chemical reactions?
Proteins in the membranes may act as enzymes
What is pseudopodia?
When plasma membranes are used for feeding and movement in single celled organisms like amobea
How does cholesterol effect the plasma membrane?
Maintains stability and fluidity
What is an amphipathic molecule? Give two examples
A molecule with hydrophilic and hydrophobic regions, phospholipids and cholesterol
How does cholesterol effect the fluidity of the plasma membrane?
It reduces the fluidity by filling the gaps when the fatty acid tail bends more and therefore prevents crystallisation
What are the components in the plasma membrane?
Phospholipids, channel proteins, carrier proteins, glycoproteins, peripheral proteins, cholesterol
What are the structural properties of the phospholipid bilayer?
7.5 nanometres thick, held by weak hydrophobic interactions, have hydrophobic and hydrophilic layers that restrict entry and exit, allow for membrane fluidity,