Membranes Flashcards
1
Q
What happens when membrane proteins are inserted?
A
- introduces asymmetry, because integral membrane proteins can move laterally (not vertically)
2
Q
What is the effect of freeze fracture?
A
- Freeze fracture splits membranes into two leaflets, freezing tightly binds phospholipids to surrounding water molecules by hydrogen bonds (in frozen state - only held together by van der wall forces)
3
Q
Diffusion
A
- passive mixing of substances resulting in net transport along concentration gradient
- random walk of individual molecules because of thermal motions and collisions (distance is proportional to root t)
- happens if there is concentration gradient, until equilibriumis reached
4
Q
Osmosis
A
- the diffusion of water
5
Q
Hypertonic
A
- a hypertonic solution is one in which there is a greater concentration or number of solute particles outside a membrane than there are inside it.
- Ocean cannot quench your thirst, water flow out of your cells to dilute
6
Q
Hypotonic
A
- tap water, net water flows in cells
- Less concentrated than the cell
7
Q
Passive vs active transport
A
- Passive: facilitate diffusion
1) Gated channel proteins: can be saturated, they must bind to substrate
2) Carrier proteins: always gates, open upon changes in electricity or binding regulators (saturation occurs much earlier than gated) - Active: transport molecules against their concentration gradient
8
Q
How does glucose carrier work?
A
- binding of sugar to either side causes a conformation change in carrier protein, transports sugar to the other side