Membrane transport Flashcards
Plasma membrane
Boundary of cell - encloses and supports cell contents
Separates intracellular vs extracellular materials
Fluid mosaic model
Attaches cells to other cells, to the surrounding matrix
Cell communicate with others through cell membrane
Determines what can move in and out of cell (selectively permeable)
Membrane potential
Channel proteins
Form tiny channel through the plasma membrane
Molecules of certain size, shape and charge can pass through
Non-gated ion channels - always open
Gated ion channels - open/closed by certain stimuli
Carrier proteins
(Transporters)
Integral proteins move ions from one side of membrane to other
- specific binding sites
- protein changes shape to transport ions or molecules
- resumes original shape after transport
- uniporters, symporters, antiporters
Solute
Dissolved substance in solution
Solvent
Liquid that holds solutes (usually water)
Solution
Mixture formed when solute is dissolved in solvent
ATP powered transport
Requires energy in the form of ATP
Transports substances against their concentration gradient, so cell can accumulate substances - sodium potassium pump
Diffusion
Molecules move from an area of higher conc to lower conc
Continues until the molecules have evenly distributed themselves throughout the solution
Diffusion through Cell Membrane
- Certain specific non-lipid soluablle molecules/ions diffuse through membrane channels
- Other non-lipid soluble molecules can’t enter cell
- Lipid soluble molecules diffuse directly though plasma membrane
Facilitated diffusion
Move large, water soluble molecule or electrically charged molecules across plasma membrane
Amino acids and glucose in, manufactured proteins out
Passive
Osmosis
Diffusion of water across a selectively permeable membrane
Effect of the concentration of the solution - determines how much water moves across the membrane
more concentrated a solution, more water will move into the solution - strong pull
Osmolarity
The pull on water created by solutes
Measured in Osmoles/L
Weak solution - low osmolarity value
Concentrated solution - high osmolarity value
Osmolarity of intracellular fluid
290 osmoles/L
Isotonic Solutions
Solution has the same osmolarity as inside of cell - water will move between cell and solution at equal rates
Hypotonic solution
Solution has lower osmolarity than cell - water moves into cell