Membrane Structure And Function 1 Flashcards
Phospholipids
Amphipatic molecule - hydrophobic and hydrophilic part
Form a bilateral w hydrophilic heads facing towards water surface and hydrophobic tails facing inwards towards the bilayer
Main components of membranes
Lipids and proteins, but also carbohydrates
Fluid mosaic model
Phosopholipid bilayer (fluid state w fatty acids - moving thing) and proteins - mosaic combo
Phsoplipid is fluid. Proteins, lipids, carbohydrates imbedd3d on it
Glycoproteins
Any protein attached to carbohydrates
Weak hydrophobic interactions generally hold membranes together
Lots of hydrophobic tails - interactions
Lipids and proteins can move sideways
Rarely flip-flop from one phospholipid layer to the other
Some proteins drift across bilayer
Some proteins (especially attached to the cytoskeleton) Move around as tho guided - directly
Membrane fluidity is influenced by temperature
Bad for the cell to be too liquid or too solid
Why our body maintains our temperature inside the body
U saturated fatty acids more fluid
More saturated more solid
Need right amount of both
And components of the membrane
Steroid cholesterol - wedged between phospholipid layers
Fluidity buffer
Helps maintain fluidity of membrane
Prevents tight packing in cold, and restrains phospholipids in warmth
Transmembrane proteins
Span the entire membrane
Integral membranes
Hydrophobic and hydrophilic part
Integral proteins
extend part way into the hydrophobic interior
Help hydrophilic molecules pass from one side of the membrane to the other hydrophilic channel
Consist of nonpolar amino acids usually coiled into a helical
Hydrophilic in contact w aqueous environment
Peripheral proteins
Not embedded in the lipid bilayer
Loosely bound to the surface of the membrane - often to integral proteins
Transport function of plasma membrane
Transportation of specific salutes into or out of the cell
Enzymatic activity - function of plasma membrane
Catalyzing 1 of a number of steps of a metabolic pathway
Signal transduction - function of plasma membrane
Relaying hormonal messages to the cell
Some transmembrane proteins attach where on the cytoplasm side
Cytoskeleton