Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Neuroscience > Membrane Potential > Flashcards

Membrane Potential Flashcards

1
Q

What is the role of the plasma membrane?

A

make separation between the extracellular and intracellular milieu

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is the role of the proteins within the phospholipid bilayer?

A
  1. help cells communicate with neighboring cells
  2. adapt to its environment
  3. sense environment
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is the essence communication within the plasma membrane?

A

transmembrane protein function and regulation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What are the ways transport across the membrane can take place?

A

diffusion, carrier proteins, and ion channels

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is the purpose of carrier proteins?

A

to help solutes that are too big or not charged cross the plasma membrane

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

How do ion channels help solutes cross the plasma membrane?

A

forms canal/water soluble channel that provides adequate environment for ions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What type of molecules can cross the membrane readily?

A

small and lipophilic molecules

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What are aquaporins?

A

ion channels that are proteins in the plasma membrane that allow H2O to flow

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is the voltage difference across the plasma membrane?

A

inside the cell: more negative
outside the cell: more positive

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

How is membrane potential created?

A

by voltage difference produced by charge gradient

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is the formula of membrane potential?

A

change in E= Em = Ein - Eout

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Is the typical resting membrane potential positive or negative?

A

negative

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What is the flow of a membrane potential?

A

rest -> depolarization -> repolarization -> rest

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Action potential is equal to …

A

change in membrane potential

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Is the movement of uncharged molecules affected by membrane potential?

A

NO

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is electrochemical potential?

A

free energy acting on charged particles

17
Q

What is the formula for electrochemical potential?

A

RT * ln (conc in. / conc. out) + zFE

18
Q

What is the nernst equation?

A

Eeq= 58z * log (conc out / conc. in); predits equilibrium potential

19
Q

What does the direction of ion movement depend on?

A

equilibrium potential and membrane potential

20
Q

At what point will the cation move into the cell?

A

when the membrane potential is more NEGATIVE

21
Q

What determines the resting membrane potential?

A

the permeabilities and conc. of Na+, K+, and Cl-

22
Q

Why is the membrane potential closest to the equilibrium potential of K+?

A

because of more K+ channels being open

23
Q

What is the Goldman equation?

A

Er = 58 * log ( Pk[Kout] + PNa [Naout] + PCl [Clin] / Pk[Kin] + PNa [Nain] + PCl [Clout]

24
Q

What is able to change the membrane potential?

A
  1. change permeability of one of the ions
  2. open or close the channels of certain ions
  3. change conc. gradient across the membrane
25
Q

When external K+ conc. is INCREASED, how does the membrane potential react?

A

gets less NEGATIVE; cell becomes depolarized

26
Q

What are the major classes of ion channels?

A
  1. leak (constitutively)
  2. stretch-activated
  3. ligand-gated
  4. voltage-gated
27
Q

What are leak activated channels?

A
  1. active channels that provide a permeation path for a specific ion
  2. maintains resting membrane potential of the cell
28
Q

What class of ion channels is responsible for maintaining the ionic composition of the intra and extracellular environments?

A

leak activated channels

29
Q

What are stretch activated channels?

A
  1. proteins change conformation when the plasma membrane is stretched
  2. aqueous pore is formed
30
Q

What occurs in a ligand gated channel?

A

neurotransmitter binds -> channel opens= flow of ions

31
Q

A voltage gated channel is …. at rest

A

closed

32
Q

What is a voltage gated channel?

A

when membrane potential is depolarized, ion channels sense voltage change and open

Neuroscience (9 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions