Meds Flashcards
zidovudine (Retrovir)
antiviral for HIV. Used to reduce transmission of HIV from a mother to fetus. Take at least six weeks after birth
Long term effects of zidovudine (Retrovir)
neutropenia and severe anemia through suppression of the bone marrow function.
hydroxurea (Droxia, Hydrea)
managing sickle cell disease to decrease the number of acute chest syndrome events, pain crises, decrease need for blood transfusions, prevents damage to organs by increasing fetal Hbg in RBC so they stay round and flexible
Education for hydroxurea (Droxia, Hydrea)
must be taken daily. will not cure SCD. Takes several months to reach the full dose - dose is started low and increased
deferasirox (Exjade)
used to lower iron from the body caused by frequent blood transfusions. The human body can’t excrete excess iron. It is stored in the liver and the heart and can cause organ damage. 2 years and older
Iron levels to measure for deferaxirox (Exjade)
Serum Ferritin test, Hepatic Iron Count
Maintains the patency of the ductus arteriosus
prostaglandin (given in ICU)
common side effects of prostaglandin
cutaneous vasodilation, bradycardia, tachycardia, hypotension, seizure-like activity, hyperthermia, and apnea
what has a faster onset and shorter duration than morphine
fentanyl
bolus dose of morphine
0.02mg/kg is the minimum dose required to produce satisfactory analgesia without causing significant SE
SE of morphine
constipation, N/V, itchiness, drowsiness, urinate a lot, mood change. Monitor RR and pattern
How do you stop morphone
slowly
given to cause vasodilation, decreases BP, improves renal blood flow
captopril, enalopril
creatinine level for newborn
0.2-1.0 mg/dL
Monitor what for captopril and enalapril
cough, renal dysfunction
decreases cardiac output, specifically treats supraventricular tachycardia/hypertension, increases contractability and excitability
propranolol, carvedilol
which meds are the opposite of digoxin
-lol meds
what do you monitor with propranolol and carvedilol
digoxin levels!!!!!!! These drugs can increase the plasma concentration of digoxin
does not spare potassium and can cause HYPOkalemia
furosemide (Lasix)
hypokalemia can increase the effects of?
digoxin
spironolactone is potassium sparing so monitor for
arrhythmias
how does digoxin work
increases force of myocardial contraction, therefore slowing HR and controls the rhythm improving tissue perfusion. Initiates diuresis and provides relief of edema. Excreted via the kidneys, however, diuretics do not affect the renal excretion of dig.
hold digoxin when HR is
below 90
the therapeutic range of dig
0.8-2.0 mg/L
best to give dig how long after feedings
1-2 hrs
digoxin is sweet so?
if the child has teeth give water after
which electrolyte should you check when giving digoxin
Potassium (normal for infant is 3.7-5.2)
S/S of digoxin toxicity
bradycardia/arrthmias, dizziness/headache, weakness and fatigue
what can increase the effects of digoxin
hypokalemia
what do Beta Blockers do to digoxin
increase the plasma concentration
med for cerebral palsy
baclofen
skeletal muscle relaxant reduces transmission of nerve impulses from spinal cord to skeletal muscles. Watch for RR issues
baclofen
inhibits action potential
GABA
