Medicine- GI Flashcards

1
Q

What is the equation for the discriminant factor in acute hepatitis and tx?

A

Discriminant factor = 4.6 x(patients PT- Control PT) + bilirubin

Tx= steroids if discriminant factor >32

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2
Q

What is orthodeoxia?

A

Hypoxia upon sitting upright (Found in hepatopulmonary syndrome)

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3
Q

In a patient with an active chronic hepatitis B infection, what tx is indicated if ALT levels are more than 2 times the upper limit or if cirrhosis is present.

A

antiviral therapy with tenofovir, entecavir, or pegylated interferon-alpha
IFN-α is, however, contraindicated among patients with autoimmune diseases such as systemic lupus erythematosus (due to exacerbation of disease)

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4
Q

Peritoneal dialysis patient, distended tender abdomen with rebound and elevated white cell count.. dx and next best step?

A

DX- Peritonitis –> next step - Gram stain of abdominal fluid

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5
Q

Most appropriate next best step in a patient with low-grade dysplasia secondary to Barrett esophagus

A

Eradication of all areas of intestinal metaplasia via endoscopic mucosal resection and subsequent endoscopic ablation therapy to remove the existing dysplasia and decrease the risk of dysplasia recurrence is the treatment of choice in patients with low-grade dysplasia.

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6
Q

What is a normal AFI

A

AFI = 8-18

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7
Q

The test of choice for confirming Boerhaave syndrome in a hemodynamically unstable patient

A

CT scan of the chest

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8
Q

Most appropriate recommendation to prevent future morbidity and mortality in patient with Variceal bleeding.

A

Endoscopic variceal ligation (EVL) should be performed every 1–2 weeks until the varices have been obliterated, after which endoscopic examination should be performed every 3–6 months.

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9
Q

Test of choice for evaluating oropharyngeal dysphagia.

A

A videofluoroscopic modified barium swallow

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10
Q

The presence of a rapidly progressive skin lesion with a characteristic necrotic base and purplish borders after minimal trauma in an individual with Crohn’s disease

A

pyoderma gangrenosum

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11
Q

Patient has biliary-type pain after cholecystectomy increased ALP and dilated common bile duct but no stones visualised… diagnosis and next best step

A

postcholecystectomy syndrome due either to residual gallstones within the biliary tree or sphincter of Oddi dysfunction.

An ERCP with sphincterotomy should be performed;

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12
Q

How does Hepatocellular carcinoma present

A

Decompensated liver failure
Weight loss
Cachexia (eg, temporal wasting)
palpable liver nodule

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13
Q

Which noninvasive lab test has high sensitivity for pancreatic exocrine insufficiency

A

Fecal Elastase

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14
Q

GI manifestations in a patient with sarcoidosis

A

Abnormal LFTs
Hepatosplenomegaly
(In a patient with Hypercalcemia and hilar adenopathy)

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15
Q

Next best step in and elderly patient with fecal incontinence

A

Assess for fecal impaction

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16
Q

Initial management for fecal impaction

A

Manual disimpaction to break up hard stool followed by Enemas

17
Q

What type of vitamin deficiency is seen in patients on long term PPIs

A

B12 (check B12 level)

18
Q

What are the complications of Primary biliary cirrhosis

A
  1. Malabsorption, Fat soluble vit deficiency
  2. osteoporosis/osteomalacia (calcium and Vit D levels will be normal)
  3. Hepatocellular carcinoma
19
Q

Causes of Pill induced esophagitis aside from bisphosphonates

A

Tetracyclines
Aspirins/ NSAIDS
Potassium Chloride
Iron

20
Q

Clinical features chronic mesenteric ischemia

A

Crampy, postprandial, epigastric pain

Food aversion and weight loss

21
Q

Diagnosis of chronic mesenteric ischemia

A

PE- abdominal bruit may be appreciated

CT angio is the preferred choice

22
Q

What Lab result is usually elevated in patients with Upper GI bleed

A

BUN and BUN/Cr ratio due to increased urea production from Hgb breakdown and increased urea absorption due to hypovolemia

23
Q

Hallmarks of secretory diarrhoea

A
  1. Larger daily stool volume (>1L/day)
  2. diarrhoea that occurs during fasting or sleep
  3. Reduced stool somatic gap (<50 mOsm/kg)