Medications (SMOs) Flashcards
Adenosine
Adenocard
Antiarrhythmic
- Slows conduction through AV node
- Interrupts AV reentry pathways
- Negative chronotrope/dromotrope
- Very short half-life (duration 30 sec)
Albuterol
Proventil, Ventolin
Bronchodilator / Beta Agonist
- Selective beta-2 agonist
- Smooth muscle relaxant (bronchodilation)
- Returns K+ into cells by activating Na-K pump at the cell membrane
Amiodarone
Cordarone
Antiarrhythmic
- Delays repolarization prolonging action potential
- Slows AV conduction, prolongs AV refractory period & QT interval, slows ventricular conduction, blocks Na/K/Ca channels and alpha/beta receptors
- Negative chronotrope/dromotrope
- Vasodilates (less cardiac workload and myocardial O2 consumption)
Acetylsalicylic acid
Aspirin
Antiplatelet agent / Salicylate
- Potent anticoagulant
- Blocks formation of thromboxane alpha-2 (prevents platelet aggregation)
- Reduces overall mortality of acute MI
- Reduces non-fatal re-infarction
Atropine
Atropen
Anticholinergic (parasympathetic blocker)
- Indirectly increase HR and AV conduction
- Decrease GI motility
- Dries secretions
- Dilates bronchioles
Diphenhydramine
Benadryl
Antihistamine (H1 blocker)
- Does not reverse histamine
- Prevents more from being released
- Not as fast as epinephrine
Benzocaine
Cetacaine, Hurricaine, Americaine
Topical anesthetic (ester type)
- Spray
- Anesthetic for mucous membranes
- Helps suppress gag reflex for intubation
Dextrose
Dextrose 10% or 25% or 50%
Antihypoglycemic, Carbohydrate
- Increases blood glucose concentrations
Diazepam
Diastat
Benzodiazepine, Sedative-hypnotic, CNS depressant, Anticonvulsant
- Rectal gel
- Suppresses seizures (precise MOA unknown)
Dopamine
Intropin
Adrenergic agonist, Inotrope, Chronotrope
- Increases HR and contractility
- At higher rates, some effect on alpha-adrenoceptors (vasoconstriction)
- Effects are dose-related, but largely depends on clinical status
Epinephrine (0.1 mg/mL)
Adrenalin
Catecholamine, Sympathetic nervous system agonist
- Alpha and beta effects
- Peripheral vasoconstrictor (increased SVR & BP)
- Makes CPR more effective (increased coronary perfusion pressure, brain perfusion, vigor/intensity of VF)
- Shortens repolarization
- May generate perfusing rhythm in asystole or bradydysrhythmias
Epinephrine (1 mg/mL)
Adrenalin
Catecholamine, Sympathetic nervous system agonist
- Beta-2 effects dominate
- Bronchodilator
- Constricts bronchial arterioles to relieve congestion & edema
- Inhibits histamine release & antagonizes effects on end organs
- Beta-1 effects (increased automaticity, HR, cardiac output, conduction)
Etomidate
Amidate
Sedative-hypnotic without analgesic effect
- Minimal effects on cardiac or respiratory symptoms
- Onset 10-20 seconds
- Duration 3-5 minutes
Fentanyl
Sublimaze
Synthetic opiate, Analgesic
- Binds to opiate receptors
- Analgesia and sedation
- Rapid onset (peak 3-5 min)
- Usual analgesic duration 30-60 min
Glucagon
GlucaGen
Antihypoglycemic agent, Hormone
- Raise blood glucose by converting liver glycogen stores to glucose
- Cardiac stimulant & positive inotrope (causes release of catecholamines & stimulates c-AMP in cells to increase CO)
- Relaxes GI smooth muscle