Med Admin Flashcards
What are the six rights of medication administration?
Right Client
Right medication
right dose
right route of administration
right time of delivery/frequency
right documentation
Why is it important to have the right client?
you don’t want the wrong patient
What are ways to check the dose?
make sure you’ve cut the pill if necessary
make sure to have the right mL, grams, mg
What are some ways you have the right medication?
it should match with the parameters such as the SBP and DBP and blood glucose levels
look to see if the medication is for the correct diagnosis
Why is it important to administer medications on time?
it maintains a consistent therapeutic blood level.
What is the window of time in which you need to administer medications for a time-critical medication?
within 30 minutes of prescribed time either before or after
What is an example of a time-critical medication?
antibiotics
What is important about documentation?
this is important to see when the last dose was given and if it was given.
If a client refuses the medication, what should the nurse do?
explain consequences, inform the provider, and document the refusal
How would you evaluate the medication’s effectiveness?(2)
follow up with therapeutic as well as adverse effects
How many times should you check the MAR?
three times
When you get the order
at the medication cart
and before giving the medication
What is important about medication reconciliation?
it ensures quality f care by reviewing the client’s current medications and addressing omissions and duplications
What is the peak of a drug’s effectiveness?
It’s the highest concentration, not necessarily at it’s most therapeutic level
What are trough serum levels?
the lowest level of concentration of a medication that correlates to the rate of elimination
What are Serious Adverse Drug Events?
severe and unexpected effects of the drug such as death, permanent disability or congenital anomaly
What should ADE be handled?
reported to FDA to imporve safety outomes, revising drug labels and warnings, and when needed, to withdraw drugs
What is a BBW?
issued on medications that may produce a lethal and iatrogenic drug
What are some drug reactions?
anaphylaxis
Stevens-Johnson Syndrome
What are symptoms of anaphylaxis? ( 3)
histamine release producing dyspnea, hypotension, and tachycardia
What is Stevens-Johnson Syndrome
occurs 1-14 days after drug administration and includes distress, fever, chills, a diffuse fine rash, and then blisters
what are common medication errors? (8)
wrong medication or IV fluid
incorrect dose or IV infusion rate
wrong client, rougt or time
administration of a medication to which the client is allergic
omission or addition of dose
incorrect discontination of med or IVE fluid
inaccurate prescribing.
What is the study of the absorption, metabolism, distribution, and excretion of drugs in the human body.
pharmacokinetics
The dissolution of a medication is dependent on (2)
initial state and route of administration.
What kind of administration are slowest?
oral/enteral
What is the process of converting a medication to a form that is easily excreted from the body.
metabolism or biotransformation
What organ metabolizes most drugs?
liver
what are some secondary organs responsible for drug metabolism?
kidneys and sections of s. intestine
prodrugs
Inactive chemicals that are transformed through metabolism to become active before they have a therapeutic effect.
How do oral meds pass through the body to get to their location?
from the small intestine to the hepatic circulation via the mesenteric vein and portal vein flowing into the liver
What does the first-pass effect do to drugs and why?
they have a lower concentration when they reach systemic circulation because their pass through the liver has made them less potent
What is the primary organ responsible for drug excretion?
kidneys
What structures exctrete medications to a lesser extent than the kidneys? (4)
skin, lungs, and exocrine glands and intestines
what is drug toxicity?
when the body is unable to metabolize and excrete a drug; drug is stuck in circulation
What do teratogenic drugs do?
cause fetal defects
What are the things that a complete medication order should contain? (8)
Client’s name
Date/time order written
Drug name (generic)
Dosage
Route of administration
Frequency-how often they receive the med
Indication for use
Provider’s signature
What should you do if the long chemical name is too long or hard to pronounce?
put the brand name
What does TORB stand for?
telephone order (has been) read back
What are generally considered high-alert medications?
with an increased risk of causing considerable client harm when they are administered in error.
What are examples of high-alert drugs?
Insulin
opiates
narcotics
intravenous heparin
injectable potassium chloride are high-alert medications.
What is one way to reduce the risk of harm with a high-alert medication?
manual independent double checks with two nurses verifying identical information before these drugs are administered.
What route is administered directly into the gastrointestinal (GI) tract
enteral
What route of administration is applied directly to the skin, mucous membranes of the eyes, nose, respiratory tract, vagina, rectum, and urinary tract
topical
What medication is administered by injection using a needle and syringe or a catheter-all injections and IV
Parenteral
What is it called if medications that can be administered between one and two hours early or late without causing harm or substandard pharmacological effects to the client?
non-time critical
What is the angle of a intramuscular injection?
90 degrees
What are examples of IM injections?
covid, vaccines, etc
What angles should the subcutaneous injections be administered?
90 if you can pinch more than 2 inches
45 if you can only pinch one inch
what are examples of intradermal injections?
TB test and allergy tests
What angles should an intradermal card be?
5 to 15
How thick is an IM injection liquid?
very viscous
Where should you place an IM shot?
ventrogluteal, deltoid, vastus lateralis
Where should you put a subcutaneous injection?
abdomen, two inches away from the belly button
upper arm
back
outer thigh
Where can intradermal injections go?
into the inner forearm back
What is ADME?
Absorption
Drug
Metabolism
Excretion
What kind of factors affect the rate of absorption? Eight.
Route of administration
Ionization
Disillusion
Blood flow
Lipid solubility
Surface area of absorptive site
Client specific factors
What is ionization of medication?
The pH of medication and the site of absorption
What are some factors that affect dissolution?
Initial state
Route of administration
Fill in the blank medication’s are absorbed more rapidly where blood flow is blank?
Blood flow is high
What are some clients specific factors that will affect absorption?
Pathophysiological processes
Diseases or injury
Gender
age
What is the rate at which the medication permeates the membranes?
Ionization
What would happen if aspirin became ionized in the small intestines alkaline environment?
It would be absorbed faster
How does a lipid solubility affect absorption?
Highly lipid-soluble medications are absorbed more rapidly than one that has low lipid solubility.
What do lipids due to medication that affect absorption?
They carry medication molecules through the membrane of blood vessels, and into the bloodstream
Why are oral medication’s designed to be absorbed in the small intestine?
Because the small intestine has a larger surface area than the stomach does
Where are enteral medication’s mostly absorbed
In the small intestine
What do mucous membranes of the G.I. tract do to medication Movement?
delay
Why do IM injections Have a faster disruption rate than subcutaneous injections?
Muscles have more blood flow than the dermis
If someone vomits after a medication is swallowed, what are some factors to consider before administering another oral dose? (3)
Time between a ministration and the vomiting episode
Presence of medication in the vomitus
Type of medication, such as extended release, or short acting
What should you do if a patient vomits after swallowing medication?
Inspector vomitus for any presence of the medication
What are some factors that affect distribution of medication in the body? (4)
Clients circulatory status
Medication solubility
protein binding ability
Permeability of the cell membrane
What are the organs of the body that receive the greatest blood supply, and therefore medication? (4)
Heart, brain, liver, and kidneys
What are some farriers in the body that prevent substances from crossing such as medication?
Blood brain barrier
Fetal placental barrier
What are some factors that can affect the absorption of oral medication? (4)
Stability and solubility of the medication
GI PH and emptying time
Presence of food in the stomach or intestines
Concurrent medication’s
Forms of medication, such as enteric-coated, pills, and liquids
What is the chemical process of converting a medication structure?
Metabolism or biotransformation
What are inactive chemicals that are activated through metabolism to exert their therapeutic affects?
Prodrugs
Why should infants be monitored when giving medication’s?
They have immature, liver function that reduces the rate of metabolism
What are two age populations that may have altered liver function, and cannot metabolize medication’s like other populations?
Infants and geriatrics
What are some physiological considerations for geriatric patients when administering medication’s?
Reduces liver function and size
Blood flow and enzyme production are slower
What does the CYP enzyme in liver do to medication metabolism
They regulate the rate at which a medication is broken down, and the amount of time the medication stays in the body
What is a method to monitor medication? Concentration in a clients blood?
Therapeutic drug monitoring
What is it called when a medication is at its highest concentration, but below the toxic level?
Peak blood level
What is the lowest level of concentration in a medication that correlates to the rate of illumination?
Trough blood level
When is the trough blood level measured?
Before administering the next schedule, dose
What is it called when a medication activates receptors to initiate a preferred response?
Agonist
What is it called when a medication prevents the activation of a receptor?
Antagonist 
What are medication thought have limited affinity to receptor sites
Partial agonist
What constitutes a serious adverse drug event?
I left threatening medication reaction that requires medical intervention to prevent death, permanent disability or congenital anomaly or causes hospitalization or belongs in hospitalization
Why must adverse drug events been reported to the FDA?
So that the agency can worked to improve safety outcomes, revise medication, labels, and warnings and withdrawal medications, if needed
What is a black box warning label
It is a label put on medication’s that may produce lethal and iatrogenic results
Iron is poorly absorbed, when taken with what type of food
Dairy or anti-acids contain magnesium
How long should medication be taken if the order recommends that to be taken on an empty stomach?
At least one hour before or two hours after a meal
What are some individuals characteristics factors that affect medication actions?
Developmental changes
Age
Weight
Gender
Culture and ethnicity
Genetics
Nutritional status
Disease status