Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Pharmacology > Mechanisms > Flashcards

Mechanisms Flashcards

1
Q

Alpha receptor agonists and antagonists

A 
Agonists = phenylephrine (sinus congestion)
antagonists = doxazosin/ tamsulosin (HTN/ BPH)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Beta 1 receptor agonists and antagonists

A 
agonists = NA
antagonists = all beta blockers eg atenolol + bisoprolol
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Beta 2 receptor agonists and antagonists

A 
agonists = salbutamol
antagonists = non selective beta blockers eg propranolol
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Dopamine receptor agonists and antagonists

A 
Agonist = parkinsons drugs 
Antagonists = anti-emetics, antipsychotics
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

GABA receptor agonists and antagonists

A 
agonists = benzodiazepines
antagonists = NA (used in benzo OD)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

H2 + H1 receptor agonists and antagonists

A

H2 antagonists = ranitidine (dyspepsia)

H1 antagonist = hayfever meds

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

muscarinic receptor agonists and antagonists

A 
agonists = pilocarpine (for glaucoma)
antagonists = atropine, ipratropium bromide (used for urge incontinence)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Zero order kinetics

A

Metabolism which is independent of concentration of reactant
Due to metabolic pathways becoming saturated

Phenytoin
High dose aspirin
Heparin
Ethanol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

PPI action

A

Inhibit H+/ K+ ATPase that transports H+ out of parietal cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What part of the brain is infarcted if you get hemiplegia/ hemiparesis?

A

Internal capsule

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Opioid agonists + antagonists

A

Agonists = opioids + loperamide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Side effects of bisphosphonates

A

Jaw osteonecrosis

Oesophagitis - take sitting up

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Serotonin antagonists + agonists

A

Antagonists: used for N+V in chemo

Agonists = rescue meds for migraine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Monitoring while on methotrexate

A

FBC, LFT, U+E

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Action of LMWH

A

Inhibits factor Xa

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

How to reverse action of LMWH

A

Protamine sulphate

17
Q

What is the SE caused by combination of statins + macrolides?

A

Myopathy

18
Q

What is the SE caused by combination of ACE inhibitors + metformin?

A

Hypoglycaemia

Pharmacology (13 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions