Common SE

Question 1

Drugs causing interstitial nephritis

Answer 1

NSAIDs

ABx

Question 2

Drugs causing acute tubular necrosis

Answer 2

Gentamicin

Lithium

Question 3

Drugs contraindicated in renal failure

Answer 3

Please Tell Nana No More ACE inhibitors

Potassium sparing diuretics 
Tetracyclines 
Nitrofurantoin 
NSAIDs
Metformin
ACE inhibitors

Question 4

Drugs that accumulate in renal failure

Answer 4

How About Stopping Opioid Drugs Accumulating

LMWH
Abx
Sulphonylureas 
Opioids 
Digoxin 
Atenolol

Question 5

Thiazide + PPI = what side effect?

Answer 5

Hyponatraemia

Question 6

Drugs metabolised by P450 + consequences of toxicity

Answer 6

Why Should The Owner Carry Drugs

Warfarin - bleeding
Statins - myopathy
Theophylline - arrhythmias + seizures
OCP - clots 
Carbamazepine - ataxia, hyponatraemia
Diltiazem + verapamil - HF

Question 7

P450 inhibitors

Answer 7

Some Drugs Are the Origin of Massive Great Concerns

Sodium valproate 
Diltiazem + verapamil 
Amiodarone
Omeprazole  
Macrolides 
Grapefruit juice 
Ciprofloxacin

Question 8

P450 inducers

Answer 8

Phenytoin
Carbamazepine 
Alcohol 
St Johns Wort 
Rifampicin

Question 9

Drugs that lower seizure threshold

Answer 9

Seizures Trick People into Thinking All Men Can Navigate Quebec

SSRIs
Tricyclic Anti- depressants 
Penicillins 
Theophylline 
Anticholinergics
Metronidazole 
Cephalosporins 
NSAIDs
Quinolones

Question 10

Drugs that prolong QT interval

Answer 10

Quite Serious Arrhythmias Maybe

Quinolones
SSRIs
Amiodarone
Macrolides

Question 11

Drugs that increase blood glucose

Answer 11

Prednisolone

Loop and thiazide diuretics

Question 12

Anticholinergic side effects

Answer 12

Dilated pupils 
Dry mouth 
Blurred vision
Urinary retention 
Constipation 

caused by PPI and TCA

Question 13

Antihistaminergic side effects

Answer 13

Weight gain
Sedation

caused by TCA

Question 14

Anti-dopaminergic side effects

Answer 14

Extrapyramidal SE eg dystonias
Oculogyric crisis

caused by metoclopramide

Question 15

Drugs causing Steven Johnson syndrome

Answer 15

Allopurinol Purpura And Swelling

Sulfonylureas
Anti-convulsants
Penicillins
Allopurinol

Question 16

Drugs causing gynaecomastia

Answer 16

Mens Tits Vary Due to Spironolactone

Metronidazole
TCAs
Verapamil 
Digoxin 
Spironolactone

Question 17

Drugs causing dyskinesia

Answer 17

Levodopa
Metoclopramide
SSRIs

Question 18

Drugs causing agranulocytosis

Answer 18

A -granulo C - ytosis

Aminosalicylates
Carbamazepine
Carbimazole

Question 19

Drugs causing neuropathy

Answer 19

Me NAP

Metronidazole
Nitrofurantoin
Amiodarone
Phenytoin

Question 20

Drugs causing liver toxicity

Answer 20

Some People Sip Pineapple Not Alcohol

Sodium valproate 
Paracetamol
Statins 
Phenytoin 
Nitrofurantoin
Amiodarone

Question 21

Drugs causing cholecystitis

Answer 21

Severe Epigastric Concern Always Occurs

Sulphonylureas 
Erythromycin 
Carbamazepine 
Amoxicillin
Opioids

Question 22

Drugs causing pulmonary toxicity

Answer 22

Amiodarone

Sulfonylureas

Question 23

Drugs causing rise in creatinine

Answer 23

Try Steroids Silly

Trimethoprim
Steroids
Salicylates

Question 24

Drugs causing photosensitivity

Answer 24

Sunshine Can Tan All Dogs

Sulphonylureas
Ciprofloxacin 
Tetracyclines 
Amiodarone 
Loop and thiazide Diuretics

Question 25

Causes and signs of hyperkalaemia

Answer 25

Muscle weakness Arrhythmias Tall tented T waves ``` Spironolactone ACE inhibitors ARBs NSAIDs Trimethoprim ``` Addisons Diabetes Hypoaldosteronism

Question 26

Causes and signs of hypokalaemia

Answer 26

Muscle cramps Bradycardia Constipation (pseudo obstruction) Thiazide diuretics Salbutamol Theophylline Steroids D+V

Question 27

Causes and signs of hypernatraemia

Answer 27

Thirsty Muscle twitching Confusion Dehydration

Question 28

Causes and signs of hyponatraemia

Answer 28

Confusion Seizures D&V Addisons HF/ cirrhosis SSRIs Sulfonylureas Loop and thiazide diuretics Carbamazepine

Question 29

Causes and signs of hypercalcaemia

Answer 29

Abdo pain Constipation Low mood Kidney stones Hyperparathyroidism Cancer

Question 30

Causes and signs of hypocalcaemia

Answer 30

Numbness Muscle spasms Bisphosphonates Hypoparathyroidism

Question 31

SE of steroids

Answer 31

``` Infection risk Proximal muscle weakness Skin thinning + bruising Mood changes Cushings if prolonged + Addisons if stopped suddenly Hypokalaemia Oedema Osteoporosis Can cause adrenal suppression + atrophy if prolonged ```

Question 32

NSAID interactions

Answer 32

Risk of bleeding/ ulcers with anticoagulants, aspirin, SSRIs + steroids Risk of renal impairment with ACEi, diuretics