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Pharmacology > Common SE > Flashcards

Common SE Flashcards

1
Q

Drugs causing interstitial nephritis

A

NSAIDs

ABx

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2
Q

Drugs causing acute tubular necrosis

A

Gentamicin

Lithium

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3
Q

Drugs contraindicated in renal failure

A

Please Tell Nana No More ACE inhibitors

Potassium sparing diuretics 
Tetracyclines 
Nitrofurantoin 
NSAIDs
Metformin
ACE inhibitors
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4
Q

Drugs that accumulate in renal failure

A

How About Stopping Opioid Drugs Accumulating

LMWH
Abx
Sulphonylureas 
Opioids 
Digoxin 
Atenolol
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5
Q

Thiazide + PPI = what side effect?

A

Hyponatraemia

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6
Q

Drugs metabolised by P450 + consequences of toxicity

A

Why Should The Owner Carry Drugs

Warfarin - bleeding
Statins - myopathy
Theophylline - arrhythmias + seizures
OCP - clots 
Carbamazepine - ataxia, hyponatraemia
Diltiazem + verapamil - HF
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7
Q

P450 inhibitors

A

Some Drugs Are the Origin of Massive Great Concerns

Sodium valproate 
Diltiazem + verapamil 
Amiodarone
Omeprazole  
Macrolides 
Grapefruit juice 
Ciprofloxacin
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8
Q

P450 inducers

A 
Phenytoin
Carbamazepine 
Alcohol 
St Johns Wort 
Rifampicin
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9
Q

Drugs that lower seizure threshold

A

Seizures Trick People into Thinking All Men Can Navigate Quebec

SSRIs
Tricyclic Anti- depressants 
Penicillins 
Theophylline 
Anticholinergics
Metronidazole 
Cephalosporins 
NSAIDs
Quinolones
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10
Q

Drugs that prolong QT interval

A

Quite Serious Arrhythmias Maybe

Quinolones
SSRIs
Amiodarone
Macrolides

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11
Q

Drugs that increase blood glucose

A

Prednisolone

Loop and thiazide diuretics

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12
Q

Anticholinergic side effects

A 
Dilated pupils 
Dry mouth 
Blurred vision
Urinary retention 
Constipation

caused by PPI and TCA

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13
Q

Antihistaminergic side effects

A

Weight gain
Sedation

caused by TCA

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14
Q

Anti-dopaminergic side effects

A

Extrapyramidal SE eg dystonias
Oculogyric crisis

caused by metoclopramide

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15
Q

Drugs causing Steven Johnson syndrome

A

Allopurinol Purpura And Swelling

Sulfonylureas
Anti-convulsants
Penicillins
Allopurinol

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16
Q

Drugs causing gynaecomastia

A

Mens Tits Vary Due to Spironolactone

Metronidazole
TCAs
Verapamil 
Digoxin 
Spironolactone
17
Q

Drugs causing dyskinesia

A

Levodopa
Metoclopramide
SSRIs

18
Q

Drugs causing agranulocytosis

A

A -granulo C - ytosis

Aminosalicylates
Carbamazepine
Carbimazole

19
Q

Drugs causing neuropathy

A

Me NAP

Metronidazole
Nitrofurantoin
Amiodarone
Phenytoin

20
Q

Drugs causing liver toxicity

A

Some People Sip Pineapple Not Alcohol

Sodium valproate 
Paracetamol
Statins 
Phenytoin 
Nitrofurantoin
Amiodarone
21
Q

Drugs causing cholecystitis

A

Severe Epigastric Concern Always Occurs

Sulphonylureas 
Erythromycin 
Carbamazepine 
Amoxicillin
Opioids
22
Q

Drugs causing pulmonary toxicity

A

Amiodarone

Sulfonylureas

23
Q

Drugs causing rise in creatinine

A

Try Steroids Silly

Trimethoprim
Steroids
Salicylates

24
Q

Drugs causing photosensitivity

A

Sunshine Can Tan All Dogs

Sulphonylureas
Ciprofloxacin 
Tetracyclines 
Amiodarone 
Loop and thiazide Diuretics
25
Q

Causes and signs of hyperkalaemia

A

Muscle weakness
Arrhythmias
Tall tented T waves

Spironolactone 
ACE inhibitors 
ARBs
NSAIDs 
Trimethoprim

Addisons
Diabetes
Hypoaldosteronism

26
Q

Causes and signs of hypokalaemia

A

Muscle cramps
Bradycardia
Constipation (pseudo obstruction)

Thiazide diuretics
Salbutamol
Theophylline
Steroids

D+V

27
Q

Causes and signs of hypernatraemia

A

Thirsty
Muscle twitching
Confusion

Dehydration

28
Q

Causes and signs of hyponatraemia

A

Confusion
Seizures

D&V
Addisons
HF/ cirrhosis

SSRIs
Sulfonylureas
Loop and thiazide diuretics
Carbamazepine

29
Q

Causes and signs of hypercalcaemia

A

Abdo pain
Constipation
Low mood
Kidney stones

Hyperparathyroidism
Cancer

30
Q

Causes and signs of hypocalcaemia

A

Numbness
Muscle spasms

Bisphosphonates
Hypoparathyroidism

31
Q

SE of steroids

A 
Infection risk
Proximal muscle weakness 
Skin thinning + bruising 
Mood changes 
Cushings if prolonged + Addisons if stopped suddenly 
Hypokalaemia 
Oedema 
Osteoporosis 
Can cause adrenal suppression + atrophy if prolonged
32
Q

NSAID interactions

A

Risk of bleeding/ ulcers with anticoagulants, aspirin, SSRIs + steroids
Risk of renal impairment with ACEi, diuretics

Pharmacology (13 decks)

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