Measuring Kidney Function Flashcards
what is used to measure kidney function
glomerular filtration rate
what is GFR
the amount of filtrate that is produced from the blood flow per unit time
what is the normal GFR
90-120 mL/min
what is the normal glomerular filtrate per day
140-180 L
what does the GFR depend on
gender, age, size of person, size of kidneys, pregnancy
how is the GFR different in babies
the GFR is lower as in uterus the mother removed waste products
when does a babies GFR become normal
by 18 months
how does the GFR change in old age
GFR declines as there is a loss of functioning nephrons
what is compensatory hypertrophy
when one kidney enlarges due to a reduction in nephron number in the other kidney
with compensatory hypertrophy is there an increase in nephron size or nephron number?
nephron size - although if it occurs early on in development you can get an increase in nephron number
does compensatory hypertrophy occur in old age when the kidneys get smaller
no
what are the risks of compensatory hypertrophy
the nephrons work hard so may wear out forming cortical scars in the kidney
what happens to the GFR in pregnancy
it increases by 50%
what does a fall in GFR mean?
kidney function in the individual has worsened
what does a rise in GFR mean?
kidney function has recovered