Controlling Blood Pressure Flashcards
what is the short term response to control blood pressure
baroreceptor response
where are baroreceptors found
in the arch of the aorta and carotid sinus
what do the baroreceptors cause to happen in the kidney
the myogenic reflex and tubuloglomerular feedback
what are the long term regulations for BP
RAAS SNS ADH ANP prostaglandins
what does ADH do
increases water reabsorption in the collecting duct through aqua porin 2 channels
what stimulates the release of ADH
increase in plasma osmolality or severe hypovolemia
what does ANP do
inhibits Na reabsorption and causes vasodilation
what is ANP released in response to
atrial stretch
what do prostaglandins do
cause vasodilation in afferent arteriole
what does the SNS do to affect BP in the kidneys
- reduces renal blood flow through vasoconstriction
- stimulates renin release
what cells produce renin
granular cells in the juxtaglomerular apparatus
what does angiotensin 2 do
causes production of aldosterone ADH release vasoconstrictor afferent and efferent arterioles sympathetic stimulation increases Na reabsorption
how does angiotensin 2 increase sodium reabsorption
binds to angiotensin 2 receptors to stimulate NHE channels
what does aldosterone do
stimulates Na and water reabsorption by activating ENaC
what cells does aldosterone work on
principal cells in the collecting duct
