MCPA Flashcards
1
Q
Etiology of Poisoning - MCPA
A
- MCPA is used as selective Herbicide and Algicide
2
Q
Mechanism of Action - MCPA
A
- Inhibits synthesis of Ribonuclease
- Uncoupling of Oxidative Phosphorylation and Demyelinisation of Peripheral Nerves
3
Q
Clinical Symptoms - MCPA
A
- Fatigue
- Vomiting and Nausea
- Diarrhoea and Anorexia
- Tremor
- Ataxia
- Increase in Body Temperature
- Hyperventilation
- Hypoxemia
- Stiffness in hinlimb muscles => Paralysis
- Coma
4
Q
Treatment - MCPA
A
- Symptomatic
- Supportive
5
Q
Chemical-Toxicological Analysis (CHTA) - MCPA
A
- TLC - Thin layer chromatography
-With Bromthymol Blue = Yellow stain on Blue background
-With AgNO3 = Dark stains under UV light
