MCPA Flashcards

1
Q

Etiology of Poisoning - MCPA

A
  • MCPA is used as selective Herbicide and Algicide
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2
Q

Mechanism of Action - MCPA

A
  • Inhibits synthesis of Ribonuclease
  • Uncoupling of Oxidative Phosphorylation and Demyelinisation of Peripheral Nerves
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3
Q

Clinical Symptoms - MCPA

A
  • Fatigue
  • Vomiting and Nausea
  • Diarrhoea and Anorexia
  • Tremor
  • Ataxia
  • Increase in Body Temperature
  • Hyperventilation
  • Hypoxemia
  • Stiffness in hinlimb muscles => Paralysis
  • Coma
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4
Q

Treatment - MCPA

A
  • Symptomatic
  • Supportive
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5
Q

Chemical-Toxicological Analysis (CHTA) - MCPA

A
  • TLC - Thin layer chromatography
    -With Bromthymol Blue = Yellow stain on Blue background
    -With AgNO3 = Dark stains under UV light
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