MATERNAL PHYSIOLOGY Flashcards
Early changes are due in part to the:
- metabolic demands brought on by the fetus, placenta and uterus
- increasing levels of pregnancy hormones particularly those of progesterone and estrogen
Late changes (starting mid-trimester) are:
- anatomical in nature
2. caused by mechanical pressure from the expanding uterus
In the nonpregnant woman, the uterus is an almost-solid structure weighing about _____ and with a cavity of _____ or less.
70 g
10 mL
By the end of pregnancy, the uterus has achieved a capacity that is _____________ times greater than in the nonpregnant state.
500 to 1000
___________ is mainly stretching & marked hypertrophy of muscle cells
Uterine enlargement
Uterus weight increases from _____ to _____ at term.
70 gm - 1100 gm
Volume of cavity is 10ml or less in non-pregnant women and increases to ______ in pregnant women
5-20 liters
For the first few weeks, the uterus maintains its original pear shape, but as pregnancy advances, the corpus and fundus assume a more globular form becoming almost spherical by _______.
12 weeks
Subsequently, the organ increases more rapidly in length than in width and assumes an _______.
ovoid shape
With ascent of the uterus from the pelvis, it usually undergoes rotation to the ______.
right
This ________ likely is caused by the rectosigmoid on the left side of the pelvis.
dextrorotation
As early as _____ after conception, the cervix begins to undergo pronounced softening and cyanosis.
1 month
Due to increased vascularity and edema of the entire cervix, together with hypertrophy and hyperplasia of the cervical glands the endocervical mucosal cells produce copious amounts of a tenacious ____ that obstruct the cervical canal soon after conception.
mucus
May act as an immunological barrier to protect the uterine contents against infection from the vagina.
Mucus plug
Rich in cytokines & immunoglobulins
Mucus plug
The major component of the cervix is ________ although it contains a small amount of smooth muscle.
connective tissue
Rearrangement of this collagen-rich connective tissue is necessary for diverse functions such as:
- maintenance of a pregnancy to term
- dilatation to aid delivery
- repair following parturition so that a successful pregnancy can be repeated
Pregnancy is associated with both endocervical gland _________ and ________ appearance.
hyperplasia and hypersecretory
Endocervical gland hyperplasia and hypersecretory appearance
Arias- Stella Reaction
_______ ceases during pregnancy, and the maturation of new follicles is suspended.
Ovulation
Ordinarily, only a single _______ can be found in pregnant women.
corpus luteum
This functions maximally during the first 6 to 7 weeks of pregnancy in progesterone production.
corpus luteum
During pregnancy, increased vascularity and hyperemia develop in the skin and muscles of the ________ and _______ with softening of the underlying abundant connective tissue.
perineum and vulva
The pH is acidic, varying from _____ due to increased production of lactic acid from glycogen in the vaginal epithelium by the action of Lactobacillus acidophilus.
3.5 to 6
Increased vascularity prominently affects the vagina and results in the violet color characteristic of ________.
Chadwick sign
HYPERPIGMENTATION
- Chloasma or Melasma Gravidarum (Mask of Pregnancy)
2. Linea Nigra
VASCULAR CHANGES
- Angiomas (vascular or spider)
2. Palmar erythema
Due to hyperestrogenemia
Palmar erythema