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Dermadessa > Mastocitoses > Flashcards

Mastocitoses Flashcards

1
Q

Quais colorações para mastócitos?

A

Azul de toluidina (azul)
Giemsa (roxo)

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2
Q

Qual melhor marcador de mastócito?

A

CD117+

Outros: CD34+ CD13+

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3
Q

Qual nome do sinal positivo na mastocitose após atrito?

A

Darier
- liberação de histamina

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4
Q

O que ajuda a diferenciar clinicamente a mastocitose na infância da mastocitose no adulto?

A

Criança: Polimorficas
Adulto: monomorficas

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5
Q

Quais são os mediadores pré formados dos mastócitos?

A

TNF alfa
Histamina
Serotonina
Aminas vasoativas
Proteases
Heparina
IL4
GM-CSF

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6
Q

Quais os mediadores de mastócitos após sua ativação?

A

Prostaglandinas, leucotrienos e TNF-alfa

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7
Q

Quais locais a mastocitose cutânea maculopapular (urticária pigmentar) geralmente poupam?

A

Poupa face, palmas e plantas

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8
Q

Qual achado clássico da mastocitose cutânea difusa?

A

Paquidermia (espessamento)

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Dermadessa (54 decks)

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