PTL - COURS 4 : Marqueurs inflammatoires Flashcards

1
Q

Médiateur : histamine
Source ?
Action ?

A

Source : basophiles, mastocytes, plaquettes
Action : VD, perm vascu

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2
Q

Médiateur : Complément
Source ?
Action ?

A

Source : foie
Action : activation chimiotaxie leucocytes, MAC, VD (par stimul mastocytes)

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3
Q

Médiateur : kinines
Source ?
Action ?

A

Source : hépatocytes
Action : VD, perm vascu, contraction mm lisse, dlr

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4
Q

Médiateur PG
Source ?
Action?

A

Source : mastocytes, leucocytes
Action : VD, dlr, fièvre

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5
Q

Médiateur LT
Source
Action

A

Source : mastocytes, leucocytes
Action : perm vascu, chimiotaxie

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6
Q

Médiateur PAF
Source
Action

A

Source mastocytes, leucocytes
Action : chimiotaxie

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7
Q

Médiateur cytokines (TNF, IL-1)
Source
Action

A

Source : macrophages, cellules endothéliales, masotyctes
Action : locale ; activation endoth
systémique ; fièvre, hypotension, choc

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8
Q

Médiateur : chimiokines
Source
Action

A

Source : leucocytes, macrophages activés
Action : chimiotaxie

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9
Q

Médiateur : NO
Source
Action

A

Source : macrophage, cellules endothéliales
Action : diminue rx inflam, bactéricide

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10
Q

Médiateur : enzymes lysosomailes
Source
Action

A

Source : macrophages, NT
Action : destruction (micro-org/tissu endommagé)

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11
Q

Médiateur ROS
Source
Action

A

Source : macrophages, NT
Action : destruction (micro-org/tissu endommagé)

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12
Q

Médiateur NP
Source
Action

A

Source : nn sensitifs, leucocytes
Action : dlr, perm vascu, tonus vascu

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13
Q

Réaction inflamm : VD
Principaux médiateurs ?

A

Histamine
PG

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14
Q

Réaction inflamm : Perm vascu
Principaux médiateurs ?

A

LT
Histamine
Complément

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15
Q

Réaction inflamm : Chimiotaxie
Principaux médiateurs ?

A

Chimiokines (TNF, IL-1)
Complément
LT

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16
Q

Réaction inflamm : Fièvre
Principaux médiateurs ?

A

Chimiokines (TNF, IL-1)
PG

17
Q

Réaction inflamm : Dlr
Principaux médiateurs ?

A

PG
NP
Bradykinines

18
Q

Réaction inflamm : dommage tissulaire
Principaux médiateurs ?

A

Enzymes lysosomiales
ROS