Marijuana Flashcards
difference between canabanoids and endocanabanoids
cannabanoids - you can consume THC CBD and mimics endocannabanoids
endocanabanoids - are naturally forming in your body
what area in the brain does canabis effect
the exectutive control areas and memory:
pre-frontal cortex
hippocampus
this is where cannabanoid receptors are dense
explain why high amounts of cannabis may be harmful in adolescents and in elderly
younger: brain is still developing
*molecular and functional altercations to behaviour and executive cognition
elder: drug-drug interations like blood thinners
Difference between CBD and THC
THC is psychoactive
-pain relief
CBD is non-psychoactive
-anti-inflammatory
THC in animal models
short and long term effects
THC disrupts signaling and plasticity.
Short term effect: impacts synaptic strength
Long-term: lasting changes in the network
THC effects on Pre-Natal exposure
- Low birth weight
- Cognition issues
- Motor issues
- Behaviour issues
- *THC can be in breast milk
- research limitations
Marajuana effects on the average human brain
-memory
-behaviour
-addiction
-impuses
-lazy
-no motivation
Marijuana effect on cerebrovascular
** increased risk of stroke (relationship with cigs)
- potential role in anthersclerosis
- stronger spice is harder on lungs (more coughing)(intense)
what is spice
synthetic cannabanoids
-stronger
-unique/unpredicable effects
-different tastes
Education and future direction —>
fig1. Vulnerability Windows: Pre-natal / gestation (early exposure)
EARLY EXPOSURE
- abnormal stress
- dysfunction in +/- pathways
- dysregulation of monoaminergic pathway
fig1. Vulnerability Windows: adolesence (late exposure)
LATE EXPOSURE
- abnormal stress
- dysfunction in +/- pathways
- dysregulation of monoaminergic pathway
-glial cells activate
- pre-frontal cortex out of sync
-too much synaptic pruning
