Alcohol Flashcards

1
Q

what part of the brain is most affected by alchohol

A

white matter (myelin on axon)

corpus callosum(connects the hemispherse),

cerebellum (motor movements)

Cerebral cortex (motor movement)

Hypothalamus (memory)

all leadingto accelerated aging

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2
Q

What effect does alcohol have on the brainq

A

dehration

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3
Q

are moderate drinkers at risk?

A

no

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4
Q

Can the white matter regrow?

A

yes. increases in cerebellar choline (important in memory)

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5
Q

is there a link between alzheimers and alcohol consumption?

A

no

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6
Q

With analysis of the neurons lost from alcohol, what size where the most common neurons lost

A

largest with somal areas of over 90 micro meters

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7
Q

the increase of ___ in the ____ ____ and _______ lead to adaptive changes of plasticity

A

hNP22, frontal cortex, hippocampus

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8
Q

what percent of alcoholics had cerebellum atrophy?

A

27% loss of purkinjie cells caused by thiamine defficency

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9
Q

what is the priciple factor causing brain damage in alcholoics

A

thiamine deficency

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10
Q

Wernickles encephlalography and Korsakoffs phychosis

A

WKS

memory disorder caused by thiamine deficincy

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11
Q

genes affect MBP and PLP?

A

yes they are involved in myelination

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