Alcohol Flashcards
what part of the brain is most affected by alchohol
white matter (myelin on axon)
corpus callosum(connects the hemispherse),
cerebellum (motor movements)
Cerebral cortex (motor movement)
Hypothalamus (memory)
all leadingto accelerated aging
What effect does alcohol have on the brainq
dehration
are moderate drinkers at risk?
no
Can the white matter regrow?
yes. increases in cerebellar choline (important in memory)
is there a link between alzheimers and alcohol consumption?
no
With analysis of the neurons lost from alcohol, what size where the most common neurons lost
largest with somal areas of over 90 micro meters
the increase of ___ in the ____ ____ and _______ lead to adaptive changes of plasticity
hNP22, frontal cortex, hippocampus
what percent of alcoholics had cerebellum atrophy?
27% loss of purkinjie cells caused by thiamine defficency
what is the priciple factor causing brain damage in alcholoics
thiamine deficency
Wernickles encephlalography and Korsakoffs phychosis
WKS
memory disorder caused by thiamine deficincy
genes affect MBP and PLP?
yes they are involved in myelination