March 19 test 1 Flashcards
What are the 2 viruses in the reovirus family?
Coltivirus–Colorado tick fever
Rotavirus–#1 cause of fatal diarrhea in children
Hypercalcemia of malignancy is most commonly associated with what cancer?
Squamous cell carcinoma of the lung
What HLA is associated with MS and what other diseases are associated with this HLA?
HLA-DR2
Hay fever
SLE
Goodpasture
What is seen on CT of an epidural hematoma and what is causing this?
Biconvex (lentiform) hyper dense blood collection
Caused by rupture of middle meningeal artery –often secondary to skull fracture
What is seen on CT of a subdural hematoma and what is causing this?
Crescent-shaped hemorrhage–crosses suture lines
Caused by rupture of bridging veins –trauma, cerebral atrophy, elderly, alcoholism, and shaken babies
When should nitazoxanide be used to tx cryptosporidium?
In immunocompetent hosts
What vasculitis is associated with transmural inflammation of the arterial wall with fibrinoid necrosis?
Polyarteritis nodosa
Associated with HBV infection
What vasculitis is associated with polymyalgia rheumatica?
Giant cell (temporal) arteritis
Hyperinsulinemia/insulin resistance is associated with what female disorder?
PCOS
What is the major difference btw IgA nephropathy and post-strep GN?
Time frame–IgA (Berger) occurs 2-3 days after URI and post-strep occurs several wks post strep infection
What is seen on brain biopsy of pt with Lewy body dementia?
a-synuclein aggregates –primarily in cortex
What electrolyte abnormalities are present in rhabdomyolysis, which can occur with neuroepileptic malignant syndrome?
Hyperkalemia–due to cell lysis and release of K
Hyperuricemia
Hyperphosphatemia
Hypocalcemia
Does osteoporosis have any gross metabolic abnormalities?
No Ca, phosphorus, Alkphos, and Mg–normal
Why is bleeding time normal in pts with hemophilia?
Bleeding time only measures platelet function and platelets are normal with hemophilia
Weil-Felix is used for dx of what disease?
Rickettsia spp.
