March 18 test 1

Question 1

What is Libman-Sacks endocarditis and what disease is it seen with?

Answer 1

Nonbacterial, verrucous thrombi usually on mitral or aortic valve

Late complication of SLE

Question 2

Name the killed vaccines…

Answer 2

Rabies
Influenza (injected)
Salk Polio
HAV

RIP Always

SalK–Killed

Question 3

Facial droop means _____ is pooped?

Answer 3

AICA–Anterior inferior cerebellar artery

Vomiting
Vertigo
Nystagmus
Paralysis of face
Decreased lacrimation and salivation
Decreased taste from anterior 2/3 of tongue
Ipsilateral decreased pain and temp on face
Contralateral decreased pain and temp on body
Ataxia
Dysmetria

Question 4

What type of cells are seen with asplenia?

Answer 4

Target cells and Howell-Jolly bodies–usually removed by the spleen–nuclei remnant

Question 5

Why are ACEi CI in pregnancy?

Answer 5

Can cause Potter syndrome –renal dysfunction in fetus

Question 6

Basilar artery infarct and other causes of damage to the ventral pons causes what?

Answer 6

Locked-in syndrome

• Preserved consciousness, vertical eye movement, blinking
• Quadriplegia, loss of voluntary facial, mouth and tongue movements

Due to damage of the corticospinal and corticobulbar tracts bilaterally

Question 7

What are the 2 causes of megaloblastic anemia?

Answer 7

Folate deficiency and Vit B12 deficiency

Folate is responsible for the 1-carbon unit transfer

Folate–no neuro symptoms
Vit B12–Neuro symptoms

Question 8

What disorder is associated with advanced paternal age and presents with small limbs and normal sized head and trunk? Due to defect in fibroblast growth factor receptor (FGFR3).

Answer 8

Achondroplasia

Question 9

What chromosomal abnormality is associated with coarctation of the aorta?

Answer 9

Turner syndrome –X0

Question 10

What is used for tx of neuroepileptic malignant syndrome?

Answer 10

Dantrolene or bromocriptine–D2 agonist

Question 11

What type of leukemia is associated with mediastinal mass?

Answer 11

Acute lymphoblastic leukemia/lymphoma

Question 12

What are the 3 metastases seen with gastric cancer?

Answer 12

Virchow node–involvement of left supraclavicular node

Krukenberg tumor–bilateral metastases to ovaires–abundant mucin-secreting, signet ring cells–associated with diffuse

Sister Mary Joseph nodule–Subcutaneous periumbilical metastasis–associated with intestinal

Question 13

What is a common finding in peripheral blood smear of a pt with multiple myeloma?

Answer 13

Rouleaux formation–RBCs stacked like poker chips in blood smear

Question 14

What leukemia is associated with DIC and Auer rods?

Answer 14

Acute myelogenous leukemia M3 type–which is acute promyelocytic leukemia

Question 15

What translocation is associated with Acute myelogenous leukemia M3 type–which is acute promyelocytic leukemia ?

Answer 15

t(15;17)

Question 16

Where are sarcomas derived from?

Answer 16

Mesenchymal origin

Question 17

What clotting factor is deficient in hemophilia A?

Answer 17

Factor VIII–increased PTT

Question 18

What clotting factor is deficient in hemophilia B?

Answer 18

Factor IX–increased PTT

Question 19

What is the common presentation of hemophilia?

Answer 19

Bleeding into joints, easy bruising, and major bleeding after trauma or surgery