Manual of Clinical Anesthesiology: IV Induction Agents Flashcards
1
Q
How does propofol affect the cardiovascular system?
A
It depresses myocardial contraction and decreases SVR, so be careful in giving to those with weak hearts.
2
Q
Propofol does what to cerebral blood flow?
A
Decreases it
3
Q
Propofol ______________ respiratory drive.
A
decreases (in 25% of people)
4
Q
Why is etomidate not given in multiple doses or for maintenance?
A
It causes adrenal suppression.
5
Q
What are two unique physiologic effects of ketamine compared to the other induction agents?
A
- It increases cerebral blood flow, while almost all others decrease it.
- It causes a sympathomimetic response, increasing SVR and HR and causing bronchodilation.
6
Q
What is the mechanism of dexmedetomidine?
A
It is an alpha-2 agonist.
(Useful for its minimal respiratory suppression and sedative effect similar to midazolam. Also, has been shown to decrease opioid requirements.)
