Manifestation of skin diseases Flashcards
What are the diagnostic criteria of SLE?
SOAP BRAIN MD
Serositis, oral ulceration, arthiritis, photosensitive rash,
Blood disorder Renal involvement (ALWASY DIPSTICK TO CHECK)
What are the skin manifestations of SLE?
Approximately 80% have skin involvement
Very common: Malar rash. Not painful, not itchy, erythematous
spare nasal folds
less common-bulbous lupus, morbilliform maculopapular rash
photosenstive rashes
what are the skin manifestation of SUBACUTE cutaneous lupus?
Annular erythematous scaly patches inflamed-can resemble psoriasis, photosensitive not painful/itchy mostly on arms and backs
what are the skin manifestation of discoid lupus
erythematous red plaques with scales-very very sticky plaques
if try to remove, leaves erosions
VERY painful
resolve with scarring and hyper pigmentation
involves
scalp/ nose/cheeks/ear lob
what are the skin manifestation of CREST syndrome
Calcinosis-hard whitish painful nodules raynauds, esophageal dysmotolity sclerodactyly teleganctasia
what are the skin manifestation of morphea
Morphea is- limited sclerosis manifestation
ONLY skin -- 2-15 c oval well defined indurated plaques initially red, but then only borders center becomes white, depressed No hair, very very dry skin is shiny
progress for 5 years, then disappear and leave brown patches
no systemic signs
most common is Gutatte morphea (what is described)
but also-pansclerotic-super large plaques
Linear morphea-long line patches
subcutaneous morphea
treat with methotrexate if not dissapearing on own
what are the skin manifestation of deratomyositis
heliotrope rash-swelling and red eyelids
gottron papules on knuckles
ragged nail cuticles and dilated blood vessels near nails
patches of blue/purple rashes
systemic -
proximal muscle weakness-hard walking etc
can have dysphagia
can also: slecrodactyly, reynauds phenomenon
if causes SOB and other—antisynthesase syndrome
find anti-Mi2/anti Jo1 (antisyntetase)
What are oedema blisters?
Appear after acute exacerbation of oedema (e.g. HF)-bullae of different sizes, filled with sterile fluids and NOT inflamed (not red, not painful, not itchy, no fevers)
different from pemphigoid– initial red itchy rashes before then small yellow bullae, inflamed
and from pemphigus-usually is mouth/mucus, and mainly see the erosions not the bullae
what is dermatitis hepetiformis
Skin manifestation of coeliac (12% of coeliac)
very polymorphic rash, with small papules, rashes, vesicles etc
nearly always red
mainly the extensor surfaces, skins, etc
patient would have diarrhoea, malabsorption bloating etc
differentials: Eczema -flexors, FHx, scabies-other people affected, etc,
bullous pemphigoid -ab testing
what is cutaneous manifestations of sarcoidosis
Lupus pernio: -large bruise plaques on nose, cheeks, ears, fingers, nose
circular plaques around body
widespread maculopapular plaques
erythema nodosum
how does vasculitis look? and causes?
Non blanching purple rashes due to heamosiderin deposition all around body
patient would be healthy in themselves
and have normal platelets (so its not ITP, or TTP)
many causes- infection, Henoch Shcolein purpura, antibiotics, etc
presentations of hence slchoein purpura
most common vasculitis in children-caused after an infection
purpura on butt and legs, colloquy abdominal pain and heamturia
adults-purpura, arthralgia, heamtururia
Iga deposits in skin-
always check kidneys
