Management Of Lung And Colorectal Cancer

Question 1

Monoclonal Abs used in treatment of lung cancer with positive EGFR mutation

Answer 1

Erlotinib, Gefitinib

Question 2

Monoclonal Abs used in treatment of lung cancer with positive ALK-EML fused gene mutation

Answer 2

Crizotinib

Question 3

Management of limited stage small cell lung cancer

Answer 3

CCRT (etoposide)
Prophylactic cranial irradiation

Question 4

Management of extensive stage small cell lung cancer

Answer 4

4-6 cycles of induction chemo+immuno followed by observation
Prophylactic cranial irradiation

Question 5

Management of Non small cell lung cancer, stage I to IIIA (N1)

Answer 5

. Surgery
. RT if inoperable
+adjuvant chemo targeted immuno

Question 6

Management of Non small cell lung cancer, stage IIIA(N2) To IIIB

Answer 6

If resectable: Neoadjuvant chemo+ PORT
If not resectable: CCRT
If pancoast tumor:
….Resectable: CCRT +SURGERY
…. Non resectable:CCRT

Question 7

Management of stage IV lung cancer

Answer 7

. Check mutation PDL1
IF >50% : IMMUNO
IF <50%: CHEMO (platinum)

. Maintenance

Question 8

Management of stage I colon cancer (Early local)

Answer 8

Surgery

Question 9

Management of stage II colon cancer (locally advanced)

Answer 9

Surgery +/- chemo

Question 10

Management of locally advanced colon cancer with LN +ve

Answer 10

Surgery + Adj. Chemo

Question 11

Management of stage IV colon or rectal cancer

Answer 11

Chemo+/- surgery

Question 12

Management of stage I rectal cancer (early local)

Answer 12

Surgery

Question 13

Management of stage II Rectal cancer (late localised)

Answer 13

الساندوتش الجراحى
. Neoadj: CTH or RT
. Surgery
. Adjuvant chemo

Question 14

A patient has been diagnosed with colon cancer stage IV , the lab tests reported that the tumor is Ras mutant, so the dr decides to give him targeted therapy.
What is the drug that the dr gave him?

Answer 14

Bevacizumab