Management of Coagulopathies

Question 1

CCM Edition 3 Chapter 105

Answer 1

Management of the bleeding patient in the ICU

Question 2

Coag prolongation to what degree usually refelect a coagulopathy

Answer 2

> 1.5–2 times the patient baseline or reference value

Question 3

What degree of coag def needs to be present for prolongation in pt and aptt

Answer 3

60%–70%

Question 4

What degree of coag def needs to be present for ACT prolongation?

Answer 4

90%

Question 5

Treatment of the Bleeding Patient

Question 6

How does DDAVP function for platlets

Answer 6

to release von Willebrand factor and factor 8 from endothelial cells.
In addition, it enhances the density of platelet surface glycoprotein receptors, thereby increasing their adhesion potential.

A dose of 1 mcg/kg subcutaneously should be considered in patients with evidence of platelet dysfunction. DDAVP administration could be repeated every 24 hours for up to 3 days, although there is about a 30% reduction in its efficacy compared with the initial administration.