Coag and Platelet monitoring

Question 1

CCM 3rd Edition

Answer 1

Chapter 186 - Coag and Platelet monitoring

Question 2

What is the normal closure time on a PFA-100

Answer 2

1-3mins
Can get cartridges with different agonists to assess different anti-platelet drugs

Question 3

How may platelet activity be assessed?

Answer 3

PFA -100
Platelet aggregometry - light transmission or electrical impedance
Flow cytometry

Question 4

What does the aPTT test for and what reagents are included?

Answer 4

intrinsic and common
Contains calcium and phospholipids

Question 5

What does the PT test for and what reagents are included?

Answer 5

extrinsic and common
tissue thromboplastin or TF and calcium

Question 6

Are D dimers and FDP useful to Dx hyperfibrinolysis ?

Answer 6

No - will not distinguish from normal clot breakdown

Question 7

Was is TEG vs ROTEM?

Answer 7

thromboelastography - cup moves around pin
rotational thromboelastometry pin moves and cup is stationary